Abstract Objective: The purpose of this study was to histologically evaluate pulp and dentin under induced tooth movement (ITM) with different types of forces. Material and Methods: The maxillary right first molars of rats were submitted to movement with continuous (CF), continuous interrupted (CIF) an...
Abstract Alveolar bone healing after upper incisor extraction in rats is a classical model of preclinical studies. The underlying morphometric, cellular and molecular mechanism, however, remains imprecise in a unique study. Objectives The aim of this study was therefore to characterize the alveolar bon...
Remodelación Ósea/fisiología,
Subunidad alfa 1 del Factor de Unión al Sitio Principal/análisis,
Expresión Génica,
Inmunohistoquímica,
Osteocalcina/análisis,
Osteopontina/análisis,
Osteoprotegerina/análisis,
Ligando RANK/análisis,
Ratas Wistar,
Valores de Referencia,
Reproducibilidad de los Resultados,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa,
Fosfatasa Ácida Tartratorresistente/análisis,
Factores de Tiempo,
Extracción Dental,
Alveolo Dental/diagnóstico por imagen,
Alveolo Dental/fisiología,
Factores de Transcripción/análisis,
Cicatrización de Heridas/fisiología,
Microtomografía por Rayos X
ABSTRACT Background: Researches on Chagas disease still use several animals and rats, due to size and susceptibility were preferred by many authors. Aim: To develop an experimental model of megacolon in rats inoculated with the strain Y of Trypanosoma cruzi. Methods: Thirty male Wistar rats were dis...
ABSTRACT Background Obtaining effective hemostasis either in the traumatic or surgical lesions of parenchymal viscera, especially the liver, has always been a challenge. Aim: Comparative study between the use of different hemostatic sponges in hepatic wound and their capacity of integration to cells i...
Vasques, Enio Rodrigues;
Cunha, José Eduardo Monteiro;
Kubrusly, Marcia Saldanha;
Coelho, Ana Maria;
Sanpietri, Sandra N;
Nader, Helena B;
Tersariol, Ivarne L S;
Lima, Marcelo A;
Chaib, Eleazar;
D'Albuquerque, Luiz Augusto Carneiro.
ABSTRACT Background: Intracellular calcium overload is known to be a precipitating factor of pancreatic cell injury in acute pancreatitis (AP). Intracellular calcium homeostasis depends of Plasmatic Membrane Calcium ATPase (PMCA), Sarcoplasmic Endothelial Reticulum Calcium ATPase 2 (SERCA 2) and the So...
Enfermedad Aguda,
Citoprotección/genética,
Disacáridos/farmacología,
Modelos Animales de Enfermedad,
Melatonina/farmacología,
Pancreatitis/inducido químicamente,
Pancreatitis/genética,
ARN Mensajero/biosíntesis,
Ratas Wistar,
ATPasas Transportadoras de Calcio del Retículo Sarcoplásmico/genética,
Intercambiador de Sodio-Calcio/genética,
Ácido Taurocólico/administración & dosificación
ABSTRACT Background: The best site for splenic implant was not defined, mainly evaluating the functionality of the implant. Aim: To evaluate the effects of autogenous splenic implantation on the subcutaneous tissue in the survival of splenectomized rats. Method: Twenty-one randomly assigned rats were ...
ABSTRACT Background: The role of autonomic nervous system in the development and maintenance of portal hypertension is not fully elucidated. It is known that the gene expression of norepinephrine in the superior mesenteric artery varies with time, and it may contribute for splanchnic vasodilation and it...
ABSTRACT Background: Peptic ulcer is considered a public health problem associated with loss of quality of life. Does not exist optimal therapeutic regimen. The search for alternative treatments using foods or plants that may assist in gastric protection may become marked in this population because of ...
ABSTRACT Background: Chronic kidney disease affects more than 500 million people worldwide. In this context, the uremic toxins present are related to worsening in tissue healing. Aim: Evaluate on healing of colonic anastomosis in uremic rats, serum and anatomopathological indicators, which may be rela...
Anastomosis Quirúrgica,
Proteína C-Reactiva/análisis,
Colágeno Tipo I/análisis,
Colágeno Tipo I/metabolismo,
Colágeno Tipo III/análisis,
Colágeno Tipo III/metabolismo,
Colon/cirugía,
Tejido de Granulación/fisiopatología,
Miofibroblastos/fisiología,
Nefrectomía,
Distribución Aleatoria,
Ratas Wistar,
Insuficiencia Renal Crónica/fisiopatología,
Herida Quirúrgica/fisiopatología,
Uremia/fisiopatología,
Cicatrización de Heridas/fisiología
RESUMO Objetivo: examinar os efeitos da sinvastatina na mucosite gástrica e intestinal após o tratamento com 5-fluorouracil (5-FU), determinados pela expressão de citocinas e histologia em ratos. Métodos: ratos pesando 270±15g foram divididos em dois grupos. O grupo 5-FU+salina foi tratado com 5-F...
Antiinflamatorios/uso terapéutico,
Biomarcadores/sangre,
Modelos Animales de Enfermedad,
Fluorouracilo/efectos adversos,
Interleucina-1beta/sangre,
Interleucina-6/sangre,
Mucosa Intestinal/efectos de los fármacos,
Mucosa Intestinal/patología,
Mucositis/inducido químicamente,
Mucositis/patología,
Mucositis/prevención & control,
Distribución Aleatoria,
Ratas Wistar,
Simvastatina/uso terapéutico,
Péptidos y Proteínas de Señalización Intercelular/sangre
