Results: 1061

Phytochemical and toxicological investigations of crude methanolic extracts, subsequent fractions and crude saponins of Isodon rugosus

Biol. Res; 47 (), 2014
BACKGROUND: Isodon rugosus is used traditionally in the management of hypertension, rheumatism, tooth-ache and pyrexia. Present study was arranged to investigate I. rugosus for phytoconstituents, phytotoxic and cytotoxic activities to explore its toxicological, pharmacological potentials and to rationali...

Extraction of saponins and toxicological profile of Teucrium stocksianum boiss extracts collected from District Swat, Pakistan

Biol. Res; 47 (), 2014
BACKGROUND: The current era is facing challenges in the management of neoplasia and weeds control. The currently available anti-cancer and herbicidal drugs are associated with some serious side effects. Therefore numerous researchers are trying to discover and develop plant based alternative particularly...

Investigations of anticholinestrase and antioxidant potentials of methanolic extract, subsequent fractions, crude saponins and flavonoids isolated from Isodon rugosus

Biol. Res; 47 (), 2014
BACKGROUND: Based on the ethnomedicinal uses and the effective outcomes of natural products in various diseases, this study was designed to evaluate Isodon rugosus as possible remedy in oxidative stress, alzheimer's and other neurodegenerative diseases. Acetylecholinestrase (AChE) and butyrylcholinestera...

In vivo and in vitro anti-inflammatory activity of Cryptostegia grandiflora Roxb. ex R. Br. leaves

Biol. Res; 47 (), 2014
BACKGROUND: Despite Cryptostegia grandiflora Roxb. ex R. Br. (Apocynaceae) leaves are widely used in folk Caribbean Colombian medicine for their anti-inflammatory effects, there are no studies that support this traditional use. Therefore, this work aimed to evaluate the effect of the total extract and pr...

Antioxidant, antimicrobial, toxicity and analgesic properties of ethanol extract of Solena amplexicaulis root

Biol. Res; 47 (), 2014
BACKGROUND: This study was subjected to investigate different pharmacological properties of ethanol extract ofSolena amplexicaulis root. RESULTS: The extract contains flavonoid, alkaloid, saponin and steroid compounds. The extract exhibited excellent antioxidant activity in DPPH radical scavenging activi...

Ethyl acetate fraction from Angelica sinensis inhibits IL-1β-induced rheumatoid synovial fibroblast proliferation and COX-2, PGE2, and MMPs production

Biol. Res; 47 (), 2014
BACKGROUND: The root of Angelica sinensis (AS), also known as "Dang-gui," was a popular herbal medicine widely used in the treatment of gynecological diseases in China, Korea, and Japan for a long time. This study aimed to determine the effects of ethyl acetate fraction from Angelica sinensis (EAAS) on t...

In vivo antipyretic, antiemetic, in vitro membrane stabilization, antimicrobial, and cytotoxic activities of different extracts from Spilanthes paniculata leaves

Biol. Res; 47 (), 2014
BACKGROUND: The study was conducted to evaluate the in vitro antimicrobial activity, cytotoxic, and membrane stabilization activities, and in vivo antiemetic and antipyretic potentials of ethanolic extract, n-hexane and ethyl acetate soluble fractions of Spilanthes paniculata leaves for the first time wi...

Estudio fitoquímico, toxicidad aguda y efectos antiulceroso y antitumoral de los extractos acuoso, etanólico y metanólico de Capsicum pubescens, «Rocoto»
Phytochemical Study, Acute Toxicity and Anti-ulcerous and Anti-tumoral Effects of the Aqueous, Ethanolic and Methanolic Extracts of Capsicum pubescens, «Rocoto»

Cultura; 28 (), 2014
Objetivo: Evaluar la composición química, la toxicidad aguda y los efectos antiulceroso y antitumoral de tres extractos de Capsicum pubescens (ROCOTO) en estudios preclínicos. Materiales y métodos: Estudio experimental preclínico, analítico. Utilizamos 50 ratas albinas machos para evaluar el efecto...

Evaluación de los principios activos de Senecio calvus en la formación de biopelículas de Pseudomonas aeruginosa
Evaluation of the active principles of Senecio calvus in the formation of biofilms of Pseudomonas aeruginosa

Los biofilms o biopelículas, comunidades complejas de microorganismos, se encuentran colonizando diferentes ambientes bióticos como abióticos; los problemas generados por estos son diversos en diferentes actividades humanas. Ya que las biopelículas son de difícil erradicación, se han planteado dive...

Evaluación de la capacidad antioxidante de los extractos etanólicos del fruto de Physalis peruviana "aguaymanto" de diferentes lugares geográficos del Perú
Evaluation of the antioxidant capacity of the ethanolic extracts of the Physalis peruviana "aguaymanto" fruit from different geographical locations of Peru

Physalis peruviana L. “aguaymanto“ es una planta nativa del Perú, utilizada en medicina tradicional por sus innumerables beneficios para la salud humana y su importante valor nutricional. La presencia de ciertos compuestos antioxidantes como los polifenoles, le atribuye la capacidad de neutralizar l...