Barlas, Aziz Mutlu;
Kismet, Kemal;
Erel, Serap;
Kuru, Serdar;
Cavusoglu, Turgut;
Senes, Mehmet;
Adiyaman, Zeynep;
Celepli, Pinar;
Hucumenoglu, Sema;
Pekcici, Recep.
Abstract Purpose: To investigate the potential protective effects of erdosteine against the harmful effects of ischemia-reperfusion injury on the liver in an experimental rat model. Methods: Forty rats were divided into 4 groups. In the sham group, only the hepatic pedicle was mobilized. No other mani...
Abstract Purpose: To evaluate the bone structure of the mandibular condyle through an animal model, after ovariectomy. Methods: Thirty-six female Wistar rats were divided into 2 groups. The OVX group was submitted to bilateral ovariectomy, the SHAM group underwent the same surgical treatment, but with...
ABSTRACT Objective: The objective of the present study was to evaluate the effectiveness of HBO therapy on biochemical parameters, renal morphology and renal scintigraphy in rats undergoing chronic unilateral partial ureteral obstruction (UPUO). Material and methods: Thirty-five rats were divided into ...
Lesión Renal Aguda/sangre,
Lesión Renal Aguda/diagnóstico por imagen,
Lesión Renal Aguda/etiología,
Lesión Renal Aguda/prevención & control,
Biomarcadores/sangre,
Modelos Animales de Enfermedad,
Oxigenoterapia Hiperbárica,
Estrés Oxidativo,
Ratas Wistar,
Obstrucción Ureteral/sangre,
Obstrucción Ureteral/complicaciones,
Obstrucción Ureteral/terapia
Abstract Introduction: The ethiopathogenesis of tympanosclerosis has not been completely under- stood yet. Recent studies have shown that free oxygen radicals are important in the formation of tympanosclerosis. Melatonin and Vitamin C are known to be a powerful antioxidant, interacts directly with React...
Vargas-Sanchez, Paula Katherine;
Moro, Marcella Goetz;
Santos, Fabio André dos;
Anbinder, Ana Lia;
Kreich, Eliane;
Moraes, Renata Mendonça;
Padilha, Lauryellen;
Kusiak, Caroline;
Scomparin, Dionizia Xavier;
Franco, Gilson Cesar Nobre.
Abstract Periodontal research involves the use of animal models to better understand the biological processes of periodontal diseases and the potential of new or existing therapies. Currently, ligature-induced periodontitis in rats is the main model used in periodontal research, in this model, alveolar b...
Pérdida de Hueso Alveolar/diagnóstico por imagen,
Pérdida de Hueso Alveolar/etiología,
Pérdida de Hueso Alveolar/patología,
Modelos Animales de Enfermedad,
Cinética,
Ligadura,
Variaciones Dependientes del Observador,
Periodontitis/diagnóstico por imagen,
Periodontitis/etiología,
Periodontitis/patología,
Radiografía Dental,
Distribución Aleatoria,
Ratas Wistar,
Valores de Referencia,
Reproducibilidad de los Resultados,
Factores de Tiempo
ABSTRACT Objectives: to verify the influence of dimethylsulfoxide and pentoxifylline on the vitality of cutaneous flaps in rats and the tissue repair process. Methods: were studied 30 Wistar rats, submitting them to a 2cm wide by 8cm long dorsal cutaneous flap, of caudal base. We distributed the anim...
ABSTRACT Objective: to evaluate whether colectomy, associated with 70% hepatectomy, influences liver regeneration in rats. Methods: we distributed 18 Wistar rats in three groups of six animals each. In group I (sham), we performed laparotomy; In group II, colectomy + 70% hepatectomy; In group III, on...
Objective: Sedation/somnolence are major side effects of pharmacotherapies for depression, and negatively affect long-term treatment compliance in depressed patients. Use of mirtazapine (MIR), an atypical antidepressant approved for the treatment of moderate to severe depression with comorbid anxiety dis...
Antidepresivos Tricíclicos/administración & dosificación,
Antidepresivos Tricíclicos/farmacología,
Peso Corporal/efectos de los fármacos,
Relación Dosis-Respuesta a Droga,
Hipnóticos y Sedantes/farmacología,
Locomoción/efectos de los fármacos,
Mianserina/administración & dosificación,
Mianserina/análogos & derivados,
Mianserina/farmacología,
Mirtazapina,
Ratas Wistar,
Prueba de Desempeño de Rotación con Aceleración Constante/métodos,
Factores de Tiempo,
Trazodona/administración & dosificación,
Trazodona/farmacología
Radiotherapy is a source of human exposure to ionizing radiation. This pure energy causes deleterious effects on tissues, which result from oxidative stress, a phenomenon in which there is the participation of the Renin-Angiotensin System (RAS). The male genital organs are extremely radiosensitive and th...
Radiación Ionizante,
Bloqueadores del Receptor Tipo 1 de Angiotensina II/administración & dosificación,
Ratas Wistar,
Testículo/efectos de los fármacos,
Testículo/ultraestructura,
Microscopía Electrónica de Transmisión,
Tamaño de los Órganos/efectos de la radiación,
Sistema Renina-Angiotensina/efectos de la radiación,
Espermatogénesis/efectos de la radiación,
Estrés Oxidativo,
Protectores contra Radiación/administración & dosificación,
Traumatismos por Radiación/prevención & control,
Testículo/efectos de la radiación
Valproic acid (VPA), an anti-epileptic drug, has been reported to cause male sub/infertility. Together with searching for alternative treatments, the degrees to which testosterone levels and sperm quality are decreased under VPA treatment also need to be clarified. This study aimed to investigate the pro...
Momordica/química,
Extractos Vegetales/administración & dosificación,
Antioxidantes/administración & dosificación,
Ácido Valproico/toxicidad,
Testículo/efectos de los fármacos,
Ratas Wistar,
Inmunohistoquímica,
Western Blotting,
Receptores Androgénicos/efectos de los fármacos,
Fosfoproteínas,
Antígeno Ki-67
