Results: 1422

Adalimumabe no manejo da retocolite ulcerativa inespecífica: resultados de um estudo multicêntrico observacional brasileiro

Arq. gastroenterol; 54 (4), 2017
ABSTRACT BACKGROUND: Adalimumab is a monoclonal antibody, tumor necrosis factor-alpha (TNFα) inhibitor that has efficacy for inducing and maintaining remission in moderate-to-severe ulcerative colitis. Real world studies with adalimumab in Latin American ulcerative colitis patients are scarce. OBJ...

Nail psoriasis treated with pulsed dye laser

An. bras. dermatol; 92 (6), 2017
Abstract: Nail changes are present in about 50% of psoriasis patients and tend to be refractory to conventional treatments. Pulsed dye laser has emerged as an alternative therapy. Our aim is to evaluate the efficacy of pulsed dye laser in nail psoriasis and the impact of treatment on quality of life. Fou...

Effects of chlorhexidine preprocedural rinse on bacteremia in periodontal patients: a randomized clinical trial

J. appl. oral sci; 25 (6), 2017
Abstract Objective: Single dose of systemic antibiotics and short-term use of mouthwashes reduce bacteremia. However, the effects of a single dose of preprocedural rinse are still controversial. This study evaluated, in periodontally diseased patients, the effects of a pre-procedural mouth rinse on indu...

Severidad de presentación de acrocordones relacionada al riesgo cardiovascular medido en función de índice de masa corporal y obesidad central
Accuracy of presentation of acrochordons related to cardiovascular risk measured according to body mass index and central obesity

Contexto: los acrocordones son protrusiones benignas de piel presentes en zonas de roce; usualmente acompañan a enfermedades metabólicas. Objetivo: caracterizar la asociación entre la severidad de presentación de acrocordones y el riesgo cardiometabólico medido en función del índice de masa corpor...

Safety and efficacy of fimasartan in Mexican patients with grade 1-2 essential hypertension

Arch. cardiol. Méx; 87 (4), 2017
Abstract: Objective: To evaluate efficacy and safety of 60 mg and 120 mg Fimasartan (FMS) alone or combined with 12.5 mg hydrochlorothiazide (HCTZ) in a Mexican population. Methods: A six month, treat-to-target, open study was conducted on subjects with grade 1-2 hypertension. The subjects were initi...

Prepubertal and postpubertal vitiligo: a multivariate comparative study in 375 patients

An. bras. dermatol; 92 (6), 2017
Abstract: Background: The onset of vitiligo during childhood is common. Limited data exist that compare the clinical associations of prepubertal and postpubertal vitiligo in Arabs. Objective: To compare the clinical profile of pre and postpubertal onset vitiligo. Methods: A cross-sectional observation...

Narrowband UV-B phototherapy in childhood atopic dermatitis: efficacy and safety

An. bras. dermatol; 92 (6), 2017
Abstract: Background: Narrow-band UVB is the most innovative steroid sparing treatment in atopic dermatitis. There are studies showing efficacy of Narrow-band UVB in childhood atopic dermatitis, but there is lack of clinical trials in the literature determining the length of remission. Therefore, we sou...

Validation of the STOP-Bang questionnaire as a means of screening for obstructive sleep apnea in adults in Brazil

J. bras. pneumol; 43 (6), 2017
ABSTRACT Objective: To validate the Portuguese-language version of the STOP-Bang (acronym for Snoring, Tiredness, Observed apnea, high blood Pressure, Body mass index, Age, Neck circumference, and Gender) questionnaire, culturally adapted for use in Brazil, as a means of screening for obstructive sleep ...

Variants in the interleukin 8 gene and the response to inhaled bronchodilators in cystic fibrosis

J. pediatr. (Rio J.); 93 (6), 2017
Abstract Objective: Interleukin 8 protein promotes inflammatory responses, even in airways. The presence of interleukin 8 gene variants causes altered inflammatory responses and possibly varied responses to inhaled bronchodilators. Thus, this study analyzed the interleukin 8 variants (rs4073, rs2227306,...

Índice clínico de gravedad en pancreatitis aguda como predictor de mortalidad en pancreatitis aguda en el servicio de urgencias

Rev. chil. cir; 69 (6), 2017
Resumen Objetivo: Determinar el BISAP como predictor de mortalidad en pancreatitis aguda en el servicio de urgencias. Materiales y métodos: Estudio de cohorte en pacientes con pancreatitis aguda atendidos en urgencias; se formaron dos grupos de acuerdo con el puntaje de BISAP, bajo riesgo (0-2) y alto...