Results: 314

Use of pharmaceutical nanotechnology for the treatment of leishmaniasis

Abstract INTRODUCTION: Leishmaniasis is a global public health concern. Currently available treatments are associated with considerable side effects. The use of nanotechnology has shown promise for improving efficacy and bioavailability and minimizing side effects. METHODS: This study investigated av...

Circulation of spotted fever group rickettsiae among dogs seropositive for Leishmania spp. in an urban area of Brazil

Abstract INTRODUCTION: Dogs play an epidemiological role in several vector-borne diseases that affect human and animal health worldwide. We aimed to identify rickettsial circulation among dogs with canine visceral leishmaniasis (CVL) from a region endemic for both diseases. METHODS: CVL-seropositive ...

Chicken eggs as a surveillance tool for malaria and leishmaniasis vector presence

Abstract INTRODUCTION: Malaria and leishmaniases are transmitted by vectors during blood-feeding. Vector-infected animals develop antibodies against the vector's saliva. This study evaluated IgY antibody detection in the chicken eggs exposed to bites from Migonemyia migonei, Lutzomyia longipalpis and A...

Nanoparticulate drug delivery systems for the treatment of neglected tropical protozoan diseases

Neglected Tropical Diseases (NTDs) comprise of a group of seventeen infectious conditions endemic in many developing countries. Among these diseases are three of protozoan origin, namely leishmaniasis, Chagas disease, and African trypanosomiasis, caused by the parasites Leishmania spp., Trypanosoma cruzi...

N-Myristoyltransferases as antileishmanial targets: a piggyback approach with benzoheterocyclic analogues

Leishmaniasis is one of the neglected diseases that remain in need for pharmacological alternatives. In this context, N-Myristoyltransferases (NMT) arise as interesting targets to explore since they are involved in the co/post-translational processing of peptides which are responsible for host cell invas...

Especies Crípticas Lutzomyia longipalpis (Diptera: Phlebotominae) y sus Implicaciones en la Transmisión de Leishmaniasis en Panamá

Rev. méd. Panamá; 39 (1), 2019
Lutzomyia longipalpis es el principal v ector de una importante enfermedad desatendida en América. La diversidad genética de este vector se estimó en la población colectada en dos áreas geográficas separadas por hasta 37 km. Analizamos la secuencia CB3­PDR / N1N­PDR de 22 individuos obte­ nie...

The sand fly species (diptera: psychodidae) in an urban environment of Mato Grosso do Sul, Brazil

Rev. patol. trop; 48 (3), 2019
The purpose of this study was to search for Lutzomyia longipalpis and Lutzomyia cruzi in the urban area of the Água Clara Municipality, Mato Grosso do Sul State, Brazil. Two CDC traps were placed in the intradomicile and the peridomicile areas in four residences once a month, for three consecutive night...

Normalización de una nueva variante de reacción en cadena de la polimerasa-hsp20 (PCR-hsp20S) útil para la detección de Leishmania

Rev. cuba. med. trop; 70 (3), 2018

Conocimientos, actitudes y prácticas para el control de enfermedades transmitidas por vectores en zona rural dispersa, San Luis de Palenque, Casanare-Colombia, 2017

Rev. med. Risaralda; 24 (2), 2018
Resumen Introducción. Ante la presencia de un probable brote asociado a IRAG Inusitado -2 casos de mortalidad notificados el 17-05-17 procedentes del área rural de San Luis de Palenque- o a enfermedad de Chagas agudo según los signos/síntomas manifestados, la Secretaría de Salud de Casanare, como ...

Relação humano-animal e leishmaniose: repercussões no cotidiano de indivíduos inseridos em região endêmica

Saúde Soc; 27 (4), 2018
Resumo No contexto das zoonoses, a premissa de que o cão é considerado pelos órgãos de saúde pública como um dos componentes da complexa cadeia de transmissão das leishmanioses (sendo recomendada sua eutanásia e, a partir de 2016, o tratamento com medicação específica se os cães forem diagnos...