Results: 182

Perfil clínico, teste padrão da resistência à droga e resultados do tratamento de pacientes com tuberculose abdominal da Índia ocidental

Arq. gastroenterol; 56 (2), 2019
ABSTRACT BACKGROUND: Abdominal tuberculosis is an increasing problem in developing world. OBJECTIVE: The objective of the study was to describe the clinical presentations, drug resistance pattern and treatment outcomes of abdominal tuberculosis in Western India. METHODS: All the cases of abdominal ...

Differences in protein expression associated with ivermectin resistance in Caenorhabditis elegans

Abstract The indiscriminate administration of synthetic anthelmintics such as ivermectin contributes to the selection of subpopulations capable of resisting the drugs' effects. To understand the mechanisms of ivermectin resistance in Caenorhabditis elegans, this study attempted to identify molecular tar...

Anthelmintic resistance of injectable macrocyclic lactones in cattle: A systematic review and meta-analysis

Abstract The purpose of this work was to identify, critically assess, and summarize available data from primary research about the anthelmintic resistance of injectable macrocyclic lactones in cattle. Meta-analysis was performed to estimate the pooled Odds Ratio and 95% Confidence Intervals. Of the 1504...

Resistencia emergente a la mupirocina en aislados de Staphylococcus aureus resistente a meticilina en un hospital pediátrico terciario en la Argentina

Arch. argent. pediatr; 117 (1), 2019
En América Latina, existen escasos estudios sobre la resistencia a mupirocina y producción de biofilm en Staphylococcus aureus resistente a la meticilina (SARM). En este trabajo, se investigó la resistencia a mupirocina en SARM aislados de pacientes pediátricos con bacteremia y su capacidad para prod...

Anti-interleukin-1 treatment among patients with familial Mediterranean fever resistant to colchicine treatment. Retrospective analysis

Säo Paulo med. j; 137 (1), 2019
ABSTRACT BACKGROUND: Up to 5% of familial Mediterranean fever (FMF) cases are unresponsive to colchicine, through resistance, side effects and toxicity. Anakinra is an alternative treatment for FMF patients whose disease remains uncontrolled with colchicine. We aimed to evaluate anti-interleukin-1 trea...

Infecciones urinarias por microorganismos multirresistentes en pacientes trasplantados renales internados

INTRODUCCIÓN: En la actualidad existe un crecimiento de infecciones urinarias en trasplantados renales, por organismos multirresistentes (OMR) que se han convertido en un desafío médico.OBJETIVO: Describir la prevalencia de infección urinaria (ITU) por OMR en pacientes trasplantados renales (PTxR) ho...

Antimony resistance in Leishmania (Viannia) braziliensis clinical isolates from atypical lesions associates with increased ARM56/ARM58 transcripts and reduced drug uptake

Mem. Inst. Oswaldo Cruz; 114 (), 2019
BACKGROUND In addition to the limited therapeutic arsenal and the side effects of antileishmanial agents, drug resistance hinders disease control. In Brazil, Leishmania braziliensis causes atypical (AT) tegumentary leishmaniasis lesions, frequently refractory to treatment. OBJECTIVES The main goal of ...

Plano de ação nacional de prevenção e controle da resistência aos antimicrobianos no âmbito da saúde única: 2018-2022

No presente documento, é apresentado o Plano Estratégico do PAN-BR (formato executivo), que contém 14 Objetivos Principais, 33 Intervenções Estratégicas e 75 Atividades, alinhados aos 5 Objetivos Estratégicos do Plano de Ação Global....

Plasmodium falciparum malarial parasites from Brazil lack artemisinin resistance-associated mutations in the kelch13 gene

Abstract INTRODUCTION Mutations in the propeller domain of the Plasmodium falciparum kelch13 (k13) gene are associated with artemisinin resistance. METHODS: We developed a PCR protocol to sequence the pfk13 gene and determined its sequence in a batch of 50 samples collected from 2003 to 2016 in Brazi...

Caracterização da tuberculose drogarresistente no Brasil, 2014

Epidemiol. serv. saúde; 28 (3), 2019
Objetivo: descrever as notificações de tuberculose drogarresistente (TB-DR) no Brasil. Métodos: estudo descritivo de características clínicas e epidemiológicas das notificações de casos de TB-DR em 2014 no SITETB e no TBWeb, sistemas de informações em que são registrados os casos sob esquema...