Results: 148

An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation

Mem. Inst. Oswaldo Cruz; 113 (6), 2018
Toxoplasma gondii uses epigenetic mechanisms to regulate both endogenous and host cell gene expression. To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins. Step 1 employs PredictNLS and NucPred to identify genes ...

Modelo socio-pedagógico de formación del Técnico Superior en Enfermería para labor de prevención
Socio-pedagogical model in Higher Technician´s Nursing Training for prevention work

Introducción: En el perfil del Técnico Superior en Enfermería se establece la formación de un técnico consciente de su práctica social y comunitaria que contribuya a aportar a la sociedad una atención con calidad y calidez. Objetivo: Proponer un modelo socio-pedagógico de formación del Técnico...

Utilização de modelos geométricos simplificados de uma córnea para fins de otimização

Rev. bras. oftalmol; 76 (6), 2017
Resumo Otimização por Enxame de Partículas (PSO) é uma técnica de inteligência artificial (AI), que pode ser usada para encontrar soluções aproximadas para problemas numéricos de maximização e minimização extremamente difíceis. Neste trabalho, utilizou-se um algoritmo PSO para comparar os d...

Distribution of stress on TMJ disc induced by use of chincup therapy: assessment by the finite element method

ABSTRACT Objective: To assess the distribution of stress produced on TMJ disc by chincup therapy, by means of the finite element method. Methods: a simplified three-dimensional TMJ disc model was developed by using Rhinoceros 3D software, and exported to ANSYS software. A 4.9N load was applied on the ...

Average interradicular sites for miniscrew insertion: should dental crowding be considered?

ABSTRACT Objective: To define a map of interradicular spaces where miniscrew can be likely placed at a level covered by attached gingiva, and to assess if a correlation between crowding and availability of space exists. Methods: Panoramic radiographs and digital models of 40 patients were selected ac...

Estimación del tiempo límite de detección del gen citocromo b de humanos en hembras de Lutzomyia evansi

Biomédica (Bogotá); 37 (supl.2), 2017
Resumen Introducción. Las técnicas de biología molecular han permitido ampliar el conocimiento sobre las fuentes de ingestión de sangre de los insectos vectores. Sin embargo, la utilidad de estas técnicas depende de la cantidad de sangre ingerida y del proceso de digestión en el insecto. Objetivo...

Effect of Occlusal Splints on the Stress Distribution on the Temporomandibular Joint Disc

Braz. dent. j; 28 (3), 2017
Abstract Conservative approach, including occlusal splint therapy, is the first option to treat temporomandibular disorders (TMD), because of its reversibility. The present study analyzed the effect of the articular disc position and occlusal splints use on the stress distribution on this disc. A two-dim...

Comparison of machine-learning algorithms to build a predictive model for detecting undiagnosed diabetes - ELSA-Brasil: accuracy study

Säo Paulo med. j; 135 (3), 2017
ABSTRACT CONTEXT AND OBJECTIVE: Type 2 diabetes is a chronic disease associated with a wide range of serious health complications that have a major impact on overall health. The aims here were to develop and validate predictive models for detecting undiagnosed diabetes using data from the Longitudinal ...

Cost-Effectiveness and Clinical Impact of Antiviral Strategies of HBeAG-Positive and Negative Chronic Hepatitis B

Ann. hepatol; 16 (3), 2017
ABSTRACT Introduction. Chronic hepatitis B (CHB) is associated with high burden and healthcare costs. Virologic response achieved with antivirals is associated with progression avoidance. This study aimed to estimate the efficiency and clinical impact of antiviral strategies in CHB patients. Material a...

Population attributable fractions for colorectal cancer and red and processed meats in Colombia - a macro-simulation study

Colomb. med; 48 (2), 2017
Abstract: Aim: to estimate the population attributable risk of consumption of red and processed meat for colorectal cancer in Colombia. Methods: to model the expected incidence of colorectal cancer in the hypothetical situation of no red and processed meat consumption in Colombia, for the year 2010. ...