Results: 122

Yolk sac primary tumor of mediastino: a rare case in a young adult

Einstein (Säo Paulo); 15 (4), 2017
ABSTRACT Germ cell tumors are rare neoplasms that mostly occur in the gonads, although they can also affect other body sites, especially the anterior mediastinum (50 to 70% of all extragonadal germ cell tumors). We report a case of a primary mediastinal yolk sac tumor, a rare and aggressive germ cell tum...

Controversies in presacral tumors management

ABSTRACT Presacral tumors are rare lesions of the retrorectal space that can present diagnostic and therapeutic difficulty because of their anatomic location and the different tissue types and etiology. Although the diagnosis and management of these tumors has evolved in recent years, several points stil...

Respuesta al tratamiento neoadyuvante con capecitabine y radioterapia en el cáncer de recto inferior localmente avanzado
Response to neoadjuvant treatment with capecitabine and radiotherapy in locally advanced lower rectal cancer

Introducción: La importancia del tratamiento neoadyuvante con quimio y radioterapia en el manejo de los tumores de recto extraperitoneal localmente avanzado ha quedado claramente demostrada. La droga que ha sido históricamente más utilizada para este fin fue el 5-Fluorouracilo (5-FU). Una nueva moléc...

Respuesta histológica completa a la neoadyuvancia en carcinoma gástrico avanzado: A propósito de un caso y revisión de la literatura

La presente comunicación, describe el primer caso en el Instituto Regional de Enfermedades Neoplásicas "Luis Pinillos Ganoza" IREN Norte en la que una paciente con carcinoma gástrico avanzado ha mostrado respuesta histopatológica completa a neoadyuvancia. Se presenta una paciente mujer de 70 años co...

La preservación del recto como alternativa en pacientes con cáncer localmente avanzado
Preserving the rectum as an alternative in patients with locally advanced cancer

Prognostic factors affecting outcomes in multivisceral en bloc resection for colorectal cancer

Clinics; 72 (5), 2017
OBJECTIVES: This study sought to determine the clinical and pathological factors associated with perioperative morbidity, mortality and oncological outcomes after multivisceral en bloc resection in patients with colorectal cancer. METHODS: Between January 2009 and February 2014, 105 patients with primar...

Breast-conserving surgery in locally advanced breast cancer submitted to neoadjuvant chemotherapy. Safety and effectiveness based on ipsilateral breast tumor recurrence and long-term follow-up

Clinics; 72 (3), 2017
OBJECTIVE: To evaluate ipsilateral breast tumor recurrence after breast-conserving surgery for locally advanced breast cancer. METHODS: A retrospective observational cohort study was performed in patients with locally advanced breast cancer submitted to breast-conserving surgery after neoadjuvant chemot...

Actividad física y cáncer de mama: un tratamiento dirigido

Rev. méd. Chile; 145 (1), 2017
In Chile breast cancer (BC) is the first cause of death in women. While the most important risk factor for its development is estrogenic stimulation, environmental factors and lifestyles also contribute to its pathogenesis. Epidemiological studies show a direct relationship between physical activity (PA)...

Genomics and epidemiology for gastric adenocarcinomas

Appl. cancer res; 37 (), 2017
Whereas the pathological aspects of Gastric Adenocarcinomas (GACs) have been well defined, the actual knowledge of its genesis and evolution remains to be translated to better diagnosis and to more effective therapeutics. As a consequence, the current treatment modalities are not yet able to modify the n...

Synergetic effects of Docetaxel and ionizing radiation reduced cell viability on MCF-7 breast cancer cell

Appl. cancer res; 37 (), 2017
Background: In recent decades neoadjuvant therapies such as combined chemotherapy and radiotherapy have been introduced for cancer management. Compared with monotherapy modalities, neoadjuvant therapy is associated with greater effectiveness while having minor side effects. Docetaxel is a chemotherapy ag...