Results: 198

Effect of focal adhesion kinase inhibition on osteoblastic cells grown on titanium with different topographies

J. appl. oral sci; 28 (), 2020
Abstract Objective The present study aimed to investigate the participation of focal adhesion kinases (FAK) in interactions between osteoblastic cells and titanium (Ti) surfaces with three different topographies, namely, untreated (US), microstructured (MS), and nanostructured (NS). Methodology Osteo...

Estudo comparativo do uso do gel de própolis e da geleia real no tratamento da mucosite oral induzida quimicamente? Estudo experimental in vivo
Comparative study of the use of propolis gel and royal jelly in the treatment of chemically induced oral mucositis? In vivo experimental study

Objetivo: Avaliar os efeitos da própolis(P) e da geleia real(GR) em comparação a terapia de fotobiomodulação (FBM) com laser de baixa intensidadeem um modelo animal de mucosite oral (MO) quimioinduzida por 5-fluorouracil (5-FU). Adicionalmente, verificar por meio de uma revisão sistemática da lite...

Avances en el conocimiento de las bases moleculares y celulares de las cardiopatías congénitas. Parte 2 y última: Cardiopatías congénitas

CorSalud; 11 (4), 2019
RESUMEN Las cardiopatías congénitas son los defectos congénitos más frecuentes en los seres humanos. Se realizó una revisión de la literatura médica con el objetivo de identificar los avances más recientes en el conocimiento de las bases moleculares y celulares de las cardiopatías congénitas. L...

L-PRF y Ciclo Celular. Revisión Narrativa

RESUMEN: Los concentrados plaquetarios han emergido como un potencial material regenerativo, utilizado de forma aislada o como andamiaje para otros materiales de injerto. Son extractos de sangre, obtenidos después de procesar una muestra de sangre completa, mediante centrifugación. El primer reporte da...

Efeito do treinamento físico no coração

O coração é um órgão que se adapta frente aos diferentes estímulos ou desafios a que é exposto. No entanto, o tipo de adaptação e a magnitude da mesma dependem do tipo, da magnitude e do tempo de duração do estímulo. Logo, a adaptação cardíaca observada após um período de treinamento fí...

Biochanin A attenuates myocardial ischemia/reperfusion injury through the TLR4/NF-κB/NLRP3 signaling pathway

Acta cir. bras; 34 (11), 2019
Abstract Purpose: Myocardial ischemia/reperfusion (Ml/R) injury is a leading cause of damage in cardiac tissues, with high rates of mortality and disability. Biochanin A (BCA) is a main constituent of Trifolium pratense L. This study was intended to explore the effect of BCA on Ml/R injury and explore t...

Insulin signaling in the whole spectrum of GH deficiency

ABSTRACT GH is one of the insulin counterregulatory hormones which acts in the opposite way to insulin, increasing the glucose production by the liver and kidneys and decreasing glucose uptake from peripheral tissues, thus being a hyperglycemic hormone. When in excess, as in acromegaly, it induces glucos...

Effects of growth hormone in the central nervous system

ABSTRACT Growth hormone (GH) is best known for its effect stimulating tissue and somatic growth through the regulation of cell division, regeneration and proliferation. However, GH-responsive neurons are spread over the entire central nervous system, suggesting that they have important roles in the brain...

New insights of growth hormone (GH) actions from tissue-specific GH receptor knockouts in mice

ABSTRACT In order to provide new insights into the various activities of GH in specific tissues, recent advances have allowed for the generation of tissue-specific GHR knockout mice. To date, 21 distinct tissue-specific mouse lines have been created and reported in 28 publications. Targeted tissues inclu...

Update on new GH-IGF axis genetic defects

ABSTRACT The somatotropic axis is the main hormonal regulator of growth. Growth hormone (GH), also known as somatotropin, and insulin-like growth factor 1 (IGF-1) are the key components of the somatotropic axis. This axis has been studied for a long time and the knowledge of how some molecules could prom...