Results: 5034

Influencia de rhBMP-2 en la reparación ósea de defectos críticos con diferentes biomateriales

Int. j. morphol; 38 (2), 2020
La regeneración de defectos óseos críticos requiere la utilización de biomateriales óseos. Así, se han utilizados agentes osteogénicos como la proteína morfogenética (rhBMP-2). El objetivo fue describir la formación ósea de defectos óseos críticos en calota de ratas utilizando rhBMP-2 con di...

Chemical characterization, antimicrobial and antioxidant activity of sugar-apple (Annona squamosa L. ) pulp extract

Rev. chil. nutr; 47 (2), 2020
Synthetic preservatives are widely present in processed foods, but most of them have carcinogenic potential, requiring the development of new natural alternatives such as fruit extracts, for microbial control. The objective of the study was to evaluate the chemical characterization, antioxidant, and anti...

Use of scanning electron microscopy in the cochlea of guinea pigs

Abstract Introduction: The use of electron microscopy in the study of the inner ear has allowed us to observe minute details of the hair cells, especially in ototoxicity studies; however, the preparation of this material is a difficult and delicate task. In an attempt to simplify the handling of these m...

Ameliorative effect of vitamin E on biochemical and ultrastructural changes in artemether-induced renal toxicity in rats

Int. j. morphol; 38 (2), 2020
This experiment was designed to study the administration of normal doses of one of recent antimalarial drug and coadministration of vitamin E on the kidney tissue. A total twenty-four adult male albino rats were used and divided into four groups: the first one served as a control, the second received art...

Reparación de lesiones musculares por incisión quirúrgica coadyuvada con una formulación basada en miel nativa (Ulmoplus®): estudio experimental en modelo animal de conejo (Pryctolagus cuniculus)

Int. j. morphol; 38 (2), 2020
Para promover la reparación y regeneración muscular, se han desarrollado diferentes estrategias, sin embargo, aún no existe un tratamiento único aceptado. Investigaciones relacionan los efectos terapéuticos de la miel en el proceso de cicatrización de heridas de diversas etiologías. Considerando l...

Addition of synthetic amino acids in sheep semen improves its quality after cryopreservation

Rev. bras. ciênc. vet; 27 (2), 2020
Some amino acids can protect mammalian sperm cells against oxidation during thermal stress caused by freezing/thawing. Thus, the objective was to evaluate the protective action of the association of the amino acids L-proline (Pro) and L-glutamine (Glu) against the cryoinjury caused to sheep sperm after c...

Coagulase-negative staphylococci: a 20-year study on the antimicrobial resistance profile of blood culture isolates from a teaching hospital

Braz. j. infect. dis; 24 (2), 2020
ABSTRACT The increasing rates of nosocomial infection associated with coagulase-negative staphylococci (CoNS) were the rationale for this study, aiming to categorize oxacillin-resistant CoNS species recovered from blood culture specimens of inpatients at the UNESP Hospital das Clínicas in Botucatu, Braz...

Nicotinamide activates latent HIV-1 ex vivo in ART suppressed individuals, revealing higher potency than the association of two methyltransferase inhibitors, chaetocin and BIX01294

Braz. j. infect. dis; 24 (2), 2020
ABSTRACT Background: Latent HIV-1 is a major hurdle in obtaining HIV-1 sustained virological remission (SVR). Here we explored histone deacetylation inhibition property of nicotinamide (NAM; n = 17) for the first time in comparison to a combination of methyltransferase inhibitors (MTIs; Chaetocin and BI...

Evaluation of in vitro activity of ceftolozane-tazobactam against recent clinical bacterial isolates from Brazil - the EM200 study

Braz. j. infect. dis; 24 (2), 2020
ABSTRACT Background: The emergence of antibiotic resistance is increasing and there are few effective antibiotics to treat infections caused by resistant and multidrug resistant bacterial pathogens. This study aimed to evaluate the in vitro activity of ceftolozane-tazobactam against clinical bacterial i...