Abstract Background and objectives: Tramadol hydrochloride is a centrally-acting synthetic opioid analgesic binding to specific opioid receptors. It is used in the management of chronic pain and is recommended as first line drug in the treatment of postoperative or orthopedic injury induced acute pain. ...
Abstract Background: Baroreceptors act as regulators of blood pressure (BP); however, its sensitivity is impaired in hypertensive patients. Among the recommendations for BP reduction, exercise training has become an important adjuvant therapy in this population. However, there are many doubts about the ...
Abstract Introduction: It is still unknown how the pharmacological inhibition of the Renin Angiotensin System (RAS) impacts the levels of inflammation and fibrosis biomarkers. Objective: This study sought to evaluate the effect of enalapril, candesartan and aliskiren on urinary levels of cytokines in a...
Amidas/farmacología,
Bloqueadores del Receptor Tipo 1 de Angiotensina II/farmacología,
Inhibidores de la Enzima Convertidora de Angiotensina/farmacología,
Bencimidazoles/farmacología,
Citocinas/orina,
Enalapril/farmacología,
Fumaratos/farmacología,
Nefrectomía,
Distribución Aleatoria,
Ratas Wistar,
Sistema Renina-Angiotensina/efectos de los fármacos,
Tetrazoles/farmacología
ABSTRACT Objective: The aim of this study was to investigate the effects of acute physical and psychological stress and temporary central nucleus of the amygdala (CeA) block on stress-induced visceral hypersensitivity. Methods: Forty two male Wistar rats were used in this study. Animals were divided in...
RESUMO Objetivo: analisar a influência da glutamina nas alterações morfo-histológicas observadas em íleo, pulmão, rim e fígado de ratos Wistar submetidos à sepse. Métodos: a sepse foi induzida por meio de ligadura e punção do ceco. Os animais foram divididos em dois grupos: grupo A, controle...
ABSTRACT Background: Extramedullary hematopoiesis depends on complex pathophysiological mechanisms linked to hematopoietic stem cells and the proteins considered mediators of the inflammation. The identification of hematopoietic cells outside bone marrow in the adult is an occurrence that can occasiona...
Pared Abdominal,
Plaquetas,
Hernia Incisional/inmunología,
Hernia Incisional/cirugía,
Inflamación/etiología,
Inflamación/inmunología,
Polímeros,
Diseño de Prótesis,
Ratas Wistar,
Bazo/citología,
Células Madre,
Mallas Quirúrgicas/efectos adversos
ABSTRACT Background: Hernia correction is a routinely performed treatment in surgical practice. The improvement of the operative technique and available materials certainly has been a great benefit to the quality of surgical results. The insertion of prostheses for hernia correction is well-founded in ...
Materiales Biocompatibles Revestidos,
Colágeno/análisis,
Diseño de Equipo,
Herniorrafia/instrumentación,
Enfermedades Peritoneales/clasificación,
Enfermedades Peritoneales/etiología,
Polipropilenos/química,
Complicaciones Posoperatorias/clasificación,
Complicaciones Posoperatorias/etiología,
Ratas Wistar,
Mallas Quirúrgicas/efectos adversos,
Adherencias Tisulares/clasificación,
Adherencias Tisulares/etiología
ABSTRACT Background: Sepsis is a potentially life-threatening complication of an infection that occurs when chemicals released into the bloodstream to fight the infection trigger inflammatory responses throughout the body, especially in the acute phase of the disease, producing excessive pro-inflammator...
ABSTRACT Background: The effects of topical application of sucralfate (SCF) on the tissue content of MUC-2 protein have not yet been evaluated in experimental models of diversion colitis. Aim: To measure the tissue content of MUC-2 protein in the colonic mucosa diverted from fecal stream submitted to t...
ABSTRACT Background: Partial hepatectomy is a surgical intervention of the liver that can trigger its regenerative process, where the residual lobes deflagrate a compensatory hyperplasia, causing its restoration almost to the original volume. Nevertheless, depending on the extent of liver damage its reg...
