Abstract Lichen sclerosus et atrophicus is a chronic disease of unknown etiology characterized by atrophic and sclerotic plaques in both genital and extragenital regions. Extensive bullous lichen sclerosus et atrophicus (BLSA) is a severe variant of the disease with no widely accepted treatment. We prese...
Vesícula/patología,
Liquen Escleroso y Atrófico/patología,
Corticoesteroides/uso terapéutico,
Biopsia,
Vesícula/tratamiento farmacológico,
Fármacos Dermatológicos/uso terapéutico,
Dermis/patología,
Doxiciclina/uso terapéutico,
Epidermis/patología,
Hidroxicloroquina/uso terapéutico,
Liquen Escleroso y Atrófico/tratamiento farmacológico,
Insuficiencia del Tratamiento
Abstract The occurrence of multiple primary melanomas in a single individual is rare. Most commonly, malignant melanocytic lesions subsequent to the initial diagnosis of melanoma are secondary cutaneous metastases. We report a patient with gastrointestinal bleeding from gastric metastasis of cutaneous me...
Neoplasias Encefálicas/secundario,
Melanoma/secundario,
Neoplasias Primarias Múltiples/patología,
Neoplasias Cutáneas/patología,
Neoplasias Gástricas/secundario,
Biopsia,
Neoplasias Encefálicas/genética,
Inhibidor p18 de las Quinasas Dependientes de la Ciclina/genética,
Dermoscopía,
Melanoma/genética,
Mutación,
Neoplasias Primarias Múltiples/genética,
Neoplasias Cutáneas/genética,
Neoplasias Gástricas/genética
Abstract Childhood linear immunoglobulin A dermatosis is a rare autoimmune vesiculobullous disease. It results in linear deposition of autoantibodies (immunoglobulin A) against antigens in the basal membrane zone, leading to subepidermal cleavage. Additional depositions of immunoglobulin G and complement...
Abstract Elastoma is a connective tissue nevus characterized by changes in elastic fibers. It can be congenital or acquired, and is usually diagnosed before puberty. Associated with osteopoikilosis, it is known as Buschke-Ollendorff syndrome. Histopathology with specific staining for elastic fibers is cr...
Abstract A 40-year-old female patient with a 5-year history of systemic lupus erythematosus was referred to our policlinic with complaints of erythema, atrophy, and telangiectasia on the upper eyelids for 8 months. No associated mucocutaneous lesion was present. Biopsy taken by our ophthalmology departme...
Abstract Leprosy is a chronic infectious disease caused by Mycobacterium leprae. This bacillus has a high predilection for skin and peripheral nerves. The scalp’s anatomical properties do not favor the development of such mycobacterium. We report a case of leprosy with scalp involvement, a rare occ...
Abstract Lucio’s phenomenon is an uncommon reaction characterized by severe necrotizing cutaneous lesions that occurs in patients with Lucio’s leprosy and lepromatous leprosy. It is considered by some authors as a variant of type 2 or 3 reaction. Death can occur because of blood dyscrasia or ...
Abstract Morbihan syndrome is a rare entity that more commonly affects women in the third or fourth decade of life. It is considered a special form of rosacea and its pathogenesis is not fully known. It is clinically characterized by the slow appearance of erythema and solid edemas on the upper portion o...
Abstract Cutaneous metastases from primary internal malignancies represent 0.7-9% of patients with cancer. We report a 65-year-old female patient referred for evaluation of normochromic papules on the trunk and upper limbs that had been present for three months. A skin biopsy revealed diffuse cutaneous i...
Abstract Linear IgA dermatosis is a rare subepidermal autoimmune blistering disease characterized by linear deposition of IgA along the basement membrane zone. In the last three decades, many different drugs have been associated with the drug-induced form of the disease, especially vancomycin. We report ...
Antibacterianos/efectos adversos,
Dermatosis Bullosa IgA Lineal/inducido químicamente,
Dermatosis Bullosa IgA Lineal/patología,
Síndrome de Stevens-Johnson/patología,
Vancomicina/efectos adversos,
Biopsia,
Diagnóstico Diferencial,
Epidermis/patología,
Técnica del Anticuerpo Fluorescente Directa,
Enfermedades Cutáneas Vesiculoampollosas/inducido químicamente,
Enfermedades Cutáneas Vesiculoampollosas/patología
