Abstract We report a 33-year-old male patient diagnosed with erythroplasia of Queyrat. The patient had an erythematous and eroded lesion affecting more than 50% of the glans associated with bleeding and local pain. Despite previous indication of penectomy, he was successfully treated with topical 5-fluor...
Antimetabolitos Antineoplásicos/administración & dosificación,
Carcinoma in Situ/tratamiento farmacológico,
Carcinoma de Células Escamosas/tratamiento farmacológico,
Eritroplasia/tratamiento farmacológico,
Fluorouracilo/administración & dosificación,
Neoplasias del Pene/tratamiento farmacológico,
Administración Tópica,
Biopsia,
Carcinoma in Situ/patología,
Carcinoma de Células Escamosas/patología,
Eritroplasia/patología,
Neoplasias del Pene/patología,
Pene/patología,
Factores de Tiempo,
Resultado del Tratamiento
Abstract Metastatic ovarian cancer uncommonly presents with skin metastasis. When present, skin metastases of ovarian cancer are usually localized in the vicinity of the primary tumor. We report a case of a 58-year-old woman with a rapid growing erythematous, well-defined nodule localized on the left nas...
Carcinoma/secundario,
Neoplasias Nasales/secundario,
Neoplasias Ováricas/patología,
Neoplasias Cutáneas/secundario,
Biopsia,
Carcinoma/diagnóstico por imagen,
Neoplasias Nasales/patología,
Neoplasias Ováricas/diagnóstico por imagen,
Piel/patología,
Neoplasias Cutáneas/patología,
Tomografía Computarizada por Rayos X
Abstract Cryptococcosis is a fungal infection caused by Cryptococcus neoformans that tends to affect immunocompromised individuals. The fungi are mostly acquired by inhalation, which leads to an initial pulmonary infection. Later, other organs - such as the central nervous system and the skin - can be af...
Criptococosis/patología,
Dermatomicosis/patología,
Huésped Inmunocomprometido,
Biopsia,
Criptococosis/inmunología,
Criptococosis/microbiología,
Cryptococcus neoformans/aislamiento & purificación,
Dermatomicosis/inmunología,
Dermatomicosis/microbiología,
Infecciones Oportunistas/microbiología,
Piel/microbiología,
Piel/patología
Abstract Tyrosine kinase inhibitors are effective as a target therapy for malignant neoplasms. Imatinib was the first tyrosine kinase inhibitor used. After its introduction, several other drugs have appeared with a similar mechanism of action, but less prone to causing resistance. Even though these drugs...
Erupciones por Medicamentos/etiología,
Erupciones por Medicamentos/patología,
Liquen Plano/patología,
Inhibidores de Proteínas Quinasas/efectos adversos,
Pirimidinas/efectos adversos,
Alopecia/inducido químicamente,
Alopecia/patología,
Antineoplásicos/efectos adversos,
Biopsia,
Mesilato de Imatinib/efectos adversos,
Leucemia Mielógena Crónica BCR-ABL Positiva/tratamiento farmacológico
Abstract Histiocytoid Sweet's Syndrome is a rare inflammatory disease described in 2005 as a variant of the classical Sweet's Syndrome (SS). Histopathologically, the dermal inflammatory infiltrate is composed mainly of mononuclear cells that have a histiocytic appearance and represent immature myeloid ce...
Abstract Acral persistent papular mucinosis (APPM) is a rare subtype of localized lichen myxedematosus. It consists of small papules localized exclusively on the back of the hands, wrists and extensor aspects of distal forearms with no other clinical or laboratory manifestations. The lesions tend to pers...
Abstract The association of mycosis fungoides and kaposi’s sarcoma in HIV-negative patients is a rare phenomenon. The presence of human herpesvirus 8 (HHV-8) – associated with all forms of Kaposi’s sarcoma – has also been recently identified in mycosis fungoides lesions. However, ...
Micosis Fungoide/complicaciones,
Micosis Fungoide/patología,
Sarcoma de Kaposi/patología,
Sarcoma de Kaposi/virología,
Neoplasias Cutáneas/patología,
Neoplasias Cutáneas/virología,
Biopsia,
Herpesvirus Humano 8/aislamiento & purificación,
Inmunohistoquímica,
Terapia de Inmunosupresión,
Micosis Fungoide/terapia,
Fototerapia,
Sarcoma de Kaposi/inmunología,
Piel/patología,
Piel/virología,
Neoplasias Cutáneas/inmunología
RESUMO O pseudotumor esclerosante de órbita é um subtipo raro de pseudotumor inflamatório idiopático de órbita. É mais comum em adultos e apresenta diagnóstico de exclusão. A primeira linha de tratamento são os esteroides. O subtipo esclerosante apresenta resposta moderada aos esteroides devido ...
Summary Adult T-cell leukemia/lymphoma (ATL) is a malignancy of mature CD4+ T-cells caused by human T-cell lymphotropic virus type 1 (HTLV-1). Twenty million people are believed to be infected throughout the world, mostly in Japan, Africa, the Caribbean, and South America, particularly in Brazil and Peru...
SUMMARY Introduction: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is an autoimmune disease that can affect multiple organs, the kidney being one of the most affected. Apart from the diagnostics value of ANCA, they have also been advocated as biomarkers of the disease activity. Rece...
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/sangre,
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/complicaciones,
Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/patología,
Anticuerpos Anticitoplasma de Neutrófilos/sangre,
Biomarcadores,
Biopsia,
Proteína C-Reactiva/análisis,
Ensayo de Inmunoadsorción Enzimática,
Riñón/patología,
Enfermedades Renales/etiología,
Enfermedades Renales/patología,
Persona de Mediana Edad,
Mieloblastina/sangre,
Peroxidasa/sangre,
Pronóstico,
Proteinuria,
Recurrencia,
Valores de Referencia,
Estudios Retrospectivos,
Estadísticas no Paramétricas
