Purpose: To investigate the effect of ellagic acid (EA) in gingival tissues injury in rats. Methods: Twenty rats were categorized into two groups. In burn group, an excisional wound area was created by removing a 4-mm diameter flap from the left molar region in the mucoperiosteal region of the gingiva. ...
Objetivos – Avaliar o potencial inibitório do ácido elágico sobre as interações do complexo Keap1-Nrf2, com o intuito de esclarecer um dos eventuais mecanismos associado à atividade antioxidante do ácido elágico. Métodos – Foram empregadas simulações de docagem molecular para prever o modo...
Abstract Ellagic acid (EA) is a phenolic biomolecule. For its biosynthesis, a source of ellagitannins is required, such as strawberries and yeasts, as precursors of the tannase and β-glucosidase enzymes responsible for hydrolysis of ellagitannins. Two experimental mixture designs were applied., varying ...
Pierote, Josué Junior Araújo;
Prieto, Lucia Trazzi;
Pires, Júlia Marques;
Câmara, João Victor Frazão;
Araújo, Cíntia Tereza Pimenta de;
Barbosa, Isabel Ferreira;
Pereira, Gisele Damiana da Silveira;
Tinoco, Justine Monteiro Monnerat;
Vianna, Renato Feres de Carvalho;
Fried, Hana;
Groisman, Sonia;
Paulillo, Luis Alexandre Maffei Sartini.
To evaluate the effect of ellagic acid on the inhibition of matrix metalloproteinase by analyzing the quality of the adhesive interface with bond strength measures in periods of 24 hours and six months of storage. Method: 40 healthy human third molars were prepared with class I cavities (5x4x3mm). The te...
Abstract The aim of this study was to determine antimicrobial activities of Alchemilla mollis, Alchemilla persica as well as ellagic acid and miquelianin against Staphylococcus aureus, Enterococcus faecalis, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans by using microbroth...
Gatto, Larissa Junqueira;
Oliveira, Gustavo Rezende Bellei de;
Rech, Katlin Suellen;
Moura, Paula Francislaine;
Gribner, Caroline;
Merino, Francis José Zortéa;
Ávila, Suelen;
Dias, Josiane de Fatima Gaspari;
Miguel, Obdulio Gomes;
Miguel, Marilis Dallarmi.
Several species of the Myrcia genus have been used in folk medicine to treat diabetes. Therefore, the aim of this work was to investigate the inhibitory activity of α-glucosidase and pancreatic lipase in the crude extract (EBF) and in the ethyl acetate fraction (FFA) of Myrcia hatschbachii, as well as t...
Myrtaceae/química,
Antioxidantes/farmacología,
Inhibidores de Glicósido Hidrolasas/farmacología,
Lipasa/efectos de los fármacos,
Páncreas/enzimología,
Extractos Vegetales/farmacología,
Extractos Vegetales/toxicidad,
Ácido Gálico,
Ácido Elágico,
Extractos Vegetales/química,
Antioxidantes/química,
Fenoles/análisis,
Difracción de Rayos X,
Depuradores de Radicales Libres,
Técnicas In Vitro,
Mezclas Complejas
Abstract Objective This study aims to evaluate the effect of ellagic acid (EA) by measuring the levels of alveolar bone resorption and inflammatory and oxidative stress markers in the periodontal tissues and serum on the periodontal repair process related to experimental periodontitis in rats. Methodo...
Abstract In this study, the effects of Ellagic acid (EA) on protein expression in yeasts and cellular development were investigated. Four groups were formed. Groups: 1) Control group; yeast only cultivated group; 2) Ellagic Acid (EA) group: EA (10%) given group; 3) Hydrogen peroxide (H2O2) Group: The gro...
Background: Biotechnological processes are part of modern industry as well as stricter environmental requirements. The need to reduce production costs and pollution demands for alternatives that involve the integral use of agro-industrial waste to produce bioactive compounds. The citrus industry generate...
Citrus sinensis/química,
Biotecnología/métodos,
Fitoquímicos,
Administración de Residuos,
Residuos/análisis,
Fermentación,
Ácido Elágico,
Aspergillus fumigatus,
Taninos Hidrolizables/análisis,
Polifenoles/análisis,
Flavonoides/análisis
ABSTRACT PURPOSE: To investigate the therapeutic effects of ellagic acid on L-arginin ınduced acute pancreatitis in rats. METHODS: Thirty-two were split into four groups. Group 1 (control) rats were performed only laparotomy, no drugs were administered. Group 2 (control+EA) rats were administered ...
Antiinflamatorios/uso terapéutico,
Antioxidantes/uso terapéutico,
Ácido Elágico/uso terapéutico,
Pancreatitis/tratamiento farmacológico,
Enfermedad Aguda,
Amilasas/sangre,
Amilasas/efectos de los fármacos,
Antiinflamatorios/farmacología,
Antioxidantes/farmacología,
Arginina,
Ácido Elágico/farmacología,
Interleucina-1beta/sangre,
Interleucina-6/sangre,
Estrés Oxidativo/efectos de los fármacos,
Pancreatitis/sangre,
Pancreatitis/inducido químicamente,
Pancreatitis/patología,
Distribución Aleatoria,
Ratas Sprague-Dawley,
Factor de Necrosis Tumoral alfa/sangre
