ABSTRACT Skin aging causes changes such as wrinkles and flaccidity leading to a large demand for aesthetic procedures, including dermal filling. A key agent in dermal filling is hyaluronic acid (HA), which is a naturally occurring glycosaminoglycan. However, it is a hydrophilic macromolecule that experie...
Abstract: Background: Heparanase is an enzyme that cleaves heparan sulfate chains. Oligosaccharides generated by heparanase induce tumor progression. Basal cell carcinoma and squamous cell carcinoma comprise types of nonmelanoma skin cancer. Objectives: Evaluate the glycosaminoglycans profile and expre...
Facial aging is a consequence of multiple intrinsic and extrinsic
interactive factors, leading to loss of volume and repositioning
of facial fat and bone remodeling. Breakthroughs have been
seen in recent decades in the ability to reduce the signs of
aging. Filling techniques and numerous products availa...
