Ursodeoxycholic acid induces sarcopenia associated with decreased protein synthesis and autophagic flux
Biol. Res; 56 (), 2023
BACKGROUND: Skeletal muscle generates force and movements and maintains posture. Under pathological conditions, muscle fibers suffer an imbalance in protein synthesis/degradation. This event causes muscle mass loss and decreased strength and muscle function, a syndrome known as sarcopenia. Recently, our ...