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Antidepressant-like effect of caffeic acid: Involvement of the cellular signaling pathways

Dalmagro, Ana Paula; Holzmann, Iandra; Zimath, Priscila Laiz; Cazarin, Camila Andre; Souza, Márcia Maria de.
Braz. J. Pharm. Sci. (Online); 58 (), 2022
Abstract Caffeic acid is a phenolic compound widely distributed in plants and beverages such as coffee. Although its mechanism of action is poorly understood, caffeic acid reportedly induces antidepressant-like and neuroprotective effects. This study aimed to investigate the involvement of cellular signa...
Antidepresivos/efectos adversos, Ácidos Cafeicos/análisis, Transducción de Señal, Café/efectos adversos, Comités de Atención Animal/clasificación, Fármacos Neuroprotectores/administración & dosificación, Plantas, Quinasas de Proteína Quinasa Activadas por Mitógenos, Prueba de Campo Abierto
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Propolis from Southwest of Parana produced by selected bees: Influence of seasonality and food supplementation on antioxidant activity and phenolic profile

CALEGARI, MATHEUS A; PRASNIEWSKI, ANA CLARA; SILVA, CLEIDIANE DA; SADO, RICARDO Y; MAIA, FABIANA M C; TONIAL, LARISSA M S; OLDONI, TATIANE L C.
An. acad. bras. ciênc; 89 (1), 2017
ABSTRACT Propolis produced by selected bees Apis mellifera were collected from March to June of 2013 and in March of 2015 and analyzed in order to evaluate the influence of climate, colony of origin, and food supplementation of colonies on the content of total phenolic and flavonoid by chromatographic an...
Antioxidantes/análisis, Abejas/fisiología, Ácidos Cafeicos/análisis, Cromatografía Líquida de Alta Presión, Ácidos Cumáricos/análisis, Suplementos Dietéticos, Flavonoides/análisis, Hidroxibenzoatos/análisis, Indicadores y Reactivos, Análisis Multivariante, Análisis de Componente Principal, Própolis/química, Valores de Referencia, Reproducibilidad de los Resultados, Estaciones del Año, Temperatura
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