El ambiente obesogénico promueve la obesidad al facilitar el acceso y consumo de una amplia variedad de alimentos palatables altos en calorías. La activación del receptor de GLP1 (GLP1R) reduce la ingesta de alimentos, enlentece el vaciamiento gástrico y promueve un balance energético negativo a tra...
Dieta/efectos adversos,
Obesidad/metabolismo,
Obesidad/etiología,
Receptor del Péptido 1 Similar al Glucagón/metabolismo,
Exenatida/administración & dosificación,
Termogénesis,
Músculo Esquelético/metabolismo,
Irinotecán,
Proteína Desacopladora 2,
Ratones Endogámicos C57BL,
Ácidos Grasos/metabolismo,
Oxidación-Reducción,
Western Blotting,
Inyecciones Intraperitoneales
The addition of different oil blends in the feed of finishing pigs was evaluated. Twenty-four castrated male finishing pigs were used in a randomized block design containing four treatments and six replicates. The treatments consisted of: Reference ration (RR) - 100% soybean oil feed; and the combination...
Introdução - Os hábitos alimentares e os nutrientes da via metabólica do folato e homocisteína possuem grande importância na manutenção da saúde. Objetivo - Investigar a relação entre padrões alimentares (PAs) e os nutrientes envolvidos nessa via metabólica, com medidas antropométricas do r...
Introdução: a epilepsia é uma doença neurológica, cuja prevalência é de 0,5 a 1% na população, sendo que 20 a 30% dos pacientes apresentam crises refratárias ao tratamento medicamentoso. A dieta cetogênica (DC) composta por alto teor de gorduras, baixo teor de carboidratos e quantidade proteic...
ABSTRACT Thraustochytrids are unicellular protists belonging to the Labyrinthulomycetes class, which are characterized by the presence of a high lipid content that could replace conventional fatty acids. They show a wide geographic distribution, however their diversity in the Antarctic Region is rather s...
Background: Mutation breeding is one of the most important routes to achieving high docosahexaenoic acid (DHA) productivity using Schizochytrium. However, few selection strategies have been reported that aim to generate a high DHA content in Schizochytrium lipids. Results: First, culture temperature alte...
Estramenopilos/metabolismo,
Ácidos Docosahexaenoicos/biosíntesis,
Mutación,
Butanoles/metabolismo,
Butanoles/toxicidad,
Estramenopilos/efectos de los fármacos,
Ácidos Grasos/metabolismo,
Biomasa,
Ácido Eicosapentaenoico/metabolismo,
Ácidos Grasos/química,
Estramenopilos/genética,
Selección Genética,
Fermentación,
Temperatura
Summary The skeletal muscle tissue has a remarkable ability to alter its plastic structural and functional properties after a harmful stimulus, regulating the expression of proteins in complex events such as muscle regeneration. In this context, considering that potential therapeutic agents have been wid...
ABSTRACT PURPOSE: To investigate the effect of curcumin on visfatin and zinc-α2-glycoprotein (ZAG) expression levels in rats with non-alcoholic fatty liver disease (NAFLD). METHODS: Fifty-six male rats were randomly divided into a control group (n=16) and model group (n=40) and were fed on a norm...
Antiinflamatorios no Esteroideos/uso terapéutico,
Curcumina/uso terapéutico,
Ácidos Grasos/metabolismo,
Nicotinamida Fosforribosiltransferasa/metabolismo,
Enfermedad del Hígado Graso no Alcohólico/metabolismo,
Proteínas de Plasma Seminal/metabolismo,
Alanina Transaminasa/sangre,
Antiinflamatorios no Esteroideos/administración & dosificación,
Antioxidantes/administración & dosificación,
Antioxidantes/uso terapéutico,
Colesterol/sangre,
Curcumina/administración & dosificación,
Modelos Animales de Enfermedad,
Evaluación Preclínica de Medicamentos,
Hígado/patología,
Enfermedad del Hígado Graso no Alcohólico/tratamiento farmacológico,
Distribución Aleatoria,
Ratas Sprague-Dawley,
Triglicéridos/sangre
Background: The paper reports on the utilization of palm kernel oil (PKO) as a low cost renewable substrate for medium-chain-length poly-3-hydroxyalkanoates (mcl-PHA) production by Pseudomonas putida BET001. Investigation on the effects of selected key variables on growth, mixed free fatty acids consumpt...
The potential of lipases (E.C.3.1.1.3.) as biocatalysts for the production of fatty acid derivatives for the food and nutraceutical industries, such as flavouring esters, fatty acid esters of antioxidants and structured lipids, is enormous, mainly due to their high regio- and stereo-selectivities, in add...
