LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

In vitro and in vivo antioxidant potentials of the methanolic crude extract from Inula glomerata Oliv. & Hiern (Asteraceae) and Salacia kraussii (Harv) Harv (Celastraceae)

Ojo, Michael C; Osunsanmi, Foluso O; Cele, Nkosinathi D; Zharare, Godfrey E; Mosa, Rebamang A; Opoku, Andy R.

Bol. latinoam. Caribe plantas med. aromát; 20 (4), 2021

Reactive oxygen species are implicated in multiple pathological conditions including erectile dysfunction. This study evaluated the in vitro and in vivo antioxidant potential of the methanolic extracts of Inula glomerata and Salacia kraussii. The plant materials were pulverized and extracted with methan...

Inula/química, Asteraceae/química, Salacia/química, Celastraceae/química, Antioxidantes/química, Antioxidantes/farmacología, Estrés Oxidativo/efectos de los fármacos, Especies Reactivas de Oxígeno, Extractos Vegetales/química, Extractos Vegetales/farmacología, Compuestos Fenólicos/análisis, Flavonoides/análisis, Fitoquímicos/análisis, Óxido Nítrico/metabolismo, Ácidos Sulfónicos/metabolismo, Benzotiazoles/metabolismo, Ratas Sprague-Dawley

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In vitro antioxidant properties, free radicals scavenging activities of extracts and polyphenol composition of a non-timber forest product used as spice: Monodora myristica

Moukette, Bruno Moukette; Pieme, Constant Anatole; Njimou, Jacques Romain; Biapa, Cabral Prosper Nya; Marco, Bravi; Ngogang, Jeanne Yonkeu.

Biol. Res; 48 (), 2015

BACKGROUND: Excessive production of free radicals causes direct damage to biological molecules such as DNA, proteins, lipids, carbohydrates leading to tumor development and progression. Natural antioxidant molecules from phytochemicals of plant origin may directly inhibit either their production or limit...

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Anticholinesterse and antioxidant investigations of crude extracts, subsequent fractions, saponins and flavonoids of atriplex laciniata L: potential effectiveness in Alzheimer's and other neurological disorders

Kamal, Zul; Ullah, Farhat; Ayaz, Muhammad; Sadiq, Abdul; Ahmad, Sajjad; Zeb, Anwar; Hussain, Abid; Imran, Muhammad.

Biol. Res; 48 (), 2015

BACKGROUND: Atriplex laciniata L. was investigated for phenolic, flavonoid contents, antioxidant, anticholinesterase activities, in an attempt to explore its effectiveness in Alzheimer's and other neurological disorders. Plant crude methanolic extract (Al.MeF), subsequent fractions; n-hexane (Al.HxF), ch...

Enfermedad de Alzheimer/tratamiento farmacológico, Antioxidantes/farmacología, Atriplex/química, Inhibidores de la Colinesterasa/farmacología, Flavonoides/metabolismo, Extractos Vegetales/farmacología, Saponinas/metabolismo, Acetilcolinesterasa/metabolismo, Antioxidantes/aislamiento & purificación, Benzotiazoles/metabolismo, Butirilcolinesterasa/metabolismo, Inhibidores de la Colinesterasa/aislamiento & purificación, Flavonoides/análisis, Depuradores de Radicales Libres/farmacología, Estrés Oxidativo/efectos de los fármacos, Fenoles/análisis, Fenoles/metabolismo, Saponinas/aislamiento & purificación, Ácidos Sulfónicos/metabolismo, Concentración 50 Inhibidora, Medicina Tradicional, Espectrofotometría

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Investigations of anticholinestrase and antioxidant potentials of methanolic extract, subsequent fractions, crude saponins and flavonoids isolated from Isodon rugosus

Zeb, Anwar; Sadiq, Abdul; Ullah, Farhat; Ahmad, Sajjad; Ayaz, Muhammad.

Biol. Res; 47 (), 2014

BACKGROUND: Based on the ethnomedicinal uses and the effective outcomes of natural products in various diseases, this study was designed to evaluate Isodon rugosus as possible remedy in oxidative stress, alzheimer's and other neurodegenerative diseases. Acetylecholinestrase (AChE) and butyrylcholinestera...

Antioxidantes/análisis, Inhibidores de la Colinesterasa/análisis, Flavonoides/análisis, Isodon/química, Extractos Vegetales/química, Saponinas/análisis, Acetilcolinesterasa/efectos de los fármacos, Benzotiazoles/metabolismo, Compuestos de Bifenilo/metabolismo, Butirilcolinesterasa/efectos de los fármacos, Flavonoides/aislamiento & purificación, Depuradores de Radicales Libres/metabolismo, Radicales Libres/análisis, Peróxido de Hidrógeno/metabolismo, Isodon/clasificación, Isodon/enzimología, Estrés Oxidativo/efectos de los fármacos, Picratos/metabolismo, Componentes Aéreos de las Plantas/química, Saponinas/aislamiento & purificación, Espectrofotometría/métodos, Ácidos Sulfónicos/metabolismo, Acetatos, Cloroformo, Mezclas Complejas, Hexanos, Concentración 50 Inhibidora, Medicina Tradicional, Metanol

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