Abstract For many centuries human populations have been suffering and trying to fight with disease-bearing mosquitoes. Emerging and reemerging diseases such as Dengue, Zika, and Chikungunya affect billions of people around the world and recently has been appealing to control with chemical pesticides. Mal...
RESUMEN Los tumores del estroma gastrointestinal (GIST) son las neoplasias mesenquimales más frecuentes del tracto digestivo. Los criterios de estadificación del riesgo, como angioinvasion, tamaño, infiltración y el índice mitótico, permiten realizar un adecuado diagnóstico y tratamiento. Se prese...
Abstract Background: The mitotic index is no longer used to classify T1 melanoma patients into T1a and T1b, so it should not be used to indicate sentinel node biopsy in these patients. Objectives: To evaluate patients with T1 melanoma who underwent sentinel lymph node biopsy and to compare those who we...
Antecedentes: En la octava edición del manual de estadificación del cáncer
del American Joint Committee on Cancer (AJCC), se introdujeron cambios
importantes en las categorías T, N y M. Al entrar en vigencia la octava guía
de la AJCC, se modificó no solo el T, sino también la indicación de biopsi...
Neoplasias Cutáneas/patología,
Estadificación de Neoplasias/métodos,
Índice Mitótico,
Biopsia del Ganglio Linfático Centinela,
Guías de Práctica Clínica como Asunto,
Estudios Transversales,
Melanoma/patología,
Melanoma/diagnóstico,
Neoplasias Cutáneas/diagnóstico,
Metástasis Linfática,
Factores de Riesgo
Today, a great interest in Jatropha-based products exists worldwide, mainly for the production of biofuel.However, the oil obtained from this plant is known to be toxic due to contained curcins andphorbol esters. Bioassays, including plant cytogenetic assays based on cell cycle observation, are...
Abstract Purpose To investigate the effects of pine needle extract (PNE) on the expression of proliferating cell nuclear antigen (PCNA) and Ki-67 during liver regeneration induced by 70% partial hepatectomy (PH) in rat. Methods Forty-eight male rats (SD, 7 weeks) had surgery (70% PH). They were randoml...
Proliferación Celular,
Hepatectomía/métodos,
Antígeno Ki-67/efectos adversos,
Antígeno Ki-67/metabolismo,
Regeneración Hepática/efectos de los fármacos,
Índice Mitótico,
Pinus/química,
Extractos Vegetales/farmacología,
Antígeno Nuclear de Célula en Proliferación/efectos de los fármacos,
Antígeno Nuclear de Célula en Proliferación/metabolismo,
Ratas Sprague-Dawley,
Factores de Tiempo
ABSTRACT Tricyclazole is currently one of the fungicides recommended for the treatment of diseases in irrigated rice. However, there is relatively little information on its cytotoxic and genotoxic potential. The objective of this study was to evaluate the cytotoxicity and genotoxicity of rice crop water ...
Riego Agrícola,
Aberraciones Cromosómicas/inducido químicamente,
Productos Agrícolas,
Productos Agrícolas/genética,
Daño del ADN,
Fungicidas Industriales,
Mitosis/efectos de los fármacos,
Índice Mitótico,
Pruebas de Mutagenicidad/métodos,
Cebollas/efectos de los fármacos,
Contaminantes Químicos del Agua/toxicidad,
Oryza/genética,
Oryza/efectos de los fármacos
Abstract Purpose: To investigate the effects of lycopene and resveratrol pretreatment on hepatic hyperplasia in partially hepatectomized rats. Methods: The lycopene group and the resveratrol group received 40 mg/kg/day of lycopene or resveratrol, respectively (dissolved in olive oil or in saline soluti...
Antioxidantes/farmacología,
Carotenoides/farmacología,
Hepatectomía/métodos,
Hígado/efectos de los fármacos,
Hígado/cirugía,
Estilbenos/farmacología,
Alanina Transaminasa/sangre,
Apoptosis/efectos de los fármacos,
Aspartato Aminotransferasas/sangre,
Hígado/enzimología,
Hígado/patología,
Regeneración Hepática/efectos de los fármacos,
Índice Mitótico,
Estrés Oxidativo/efectos de los fármacos,
Ratas Wistar,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Resultado del Tratamiento
Abstract Despite their great importance for the food industry, flavorings, in general, raise a number of questions regarding their cytotoxicity, mutagenicity and carcinogenicity, since, in the literature, there are few studies found evaluating the toxicity on the systemic and cellular level, of these che...
Abstract The objective of this study was to evaluate the action of Hymenaea stigonocarpa bark hydroalcoholic extract against a mutagenic compound using A. cepa meristematic root cells as a test system. The treatment groups were: Negative Control (NC) – distilled water; Positive Control (PC) –...
Acetaminofén/farmacología,
Antimitóticos/farmacología,
Antipiréticos/farmacología,
Ciclo Celular/efectos de los fármacos,
Hymenaea,
Meristema,
Índice Mitótico/métodos,
Mutágenos/metabolismo,
Mutágenos/farmacología,
Cebollas/citología,
Cebollas/fisiología,
Corteza de la Planta,
Extractos Vegetales/farmacología,
Factores de Tiempo
