SUMMARY: Mormodica balsamina is a valuable medicinal plant that is used to treat wounds and inflammation; its leaves are also used as an antibiotic and in the treatment of stomach pain. This study was conducted to determine the anti-ulcer activity of methanolic leaf extract of Mormodica balsamina on etha...
Momordica/química,
Momordica balsamica,
Extractos Vegetales/administración & dosificación,
Hojas de la Planta,
Etanol/toxicidad,
Úlcera Gástrica/tratamiento farmacológico,
Mucosa Gástrica/efectos de los fármacos,
Plantas Medicinales,
Úlcera Gástrica/inducido químicamente,
Extractos Vegetales/química,
Antiulcerosos/administración & dosificación,
Antiulcerosos/química,
Modelos Animales de Enfermedad
Altaf, Sidra;
Abbas, Rao Zahid;
Akhtar, Tayyaba;
Siddique, Faisal;
Mahmood, Muhammad Shahid;
Khan, Muhammad Kasib;
Ziaf, Khurram;
Rafay, Muhammad;
Khan, Muhammad Azam;
Abbas, Asghar;
ur Rehman, Tauseef;
Aguilar Marcelino, Liliana;
Zia, Muhammad;
Khater, Hanem Fathy;
Saeed, Nahla Muhammad;
Abbasi, Karim Yar.
Oxidative stress is a key cause of gastrointestinal disorders, primarily stomach ulcers. Multiple intrinsic and extrinsic mechanisms caused the body to produce reactive oxygen species (ROS). The body's antioxidant defense system protects against these reactive species. When the degree of ROS ...
The objective of this work was to evaluate the gastroprotective activity of the crude ethanolic extract (CEE) from the stem barks of Piptadenia viridiflora using the acute models of inducing gastric ulcers by ethanol, ethanol-acidified, and ischemia-reperfusion, and correlating thi...
Monteverdia ilicifolia, conhecida popularmente como espinheira-santa, é uma planta da família Celastraceae de relevante ação terapêutica devido às suas propriedades medicinais, principalmente a sua atividade gastroprotetora, possuindo efeitos comprovados sobre acidez e úlceras estomacais. Desta fo...
Solanum nigrum (SLN), commonly known as African nightshade, is used as a vegetable as well as in the management and treatment of various ailments including gastric ulcers. We analyzed, both grossly and microscopically using H&E, Masson's trichrome and PSA staining methods, the protective effects of a...
Se evaluó la actividad gastroprotectora de la infusión proveniente de las hojas de Aloysia gratissima (Verbenaceae), especie nativa de interés medicinal que se desarrolla en el sudoeste bonaerense, utilizando un modelo de inducción de úlceras gástricas con etanol en ratones. Se realizó un tamizaje...
Abstract Purpose: To investigate the gastroprotective effect of methanol extract of E. spectabilis and its major component isoorientin. Methods: Effects of isoorientin and methanol extract of E. spectabilis were investigated in indomethacin-induced gastric damage model on rats. Famotidine was used as...
Antiulcerosos/farmacología,
Antioxidantes/farmacología,
Relación Dosis-Respuesta a Droga,
Glutatión/análisis,
Glutatión/efectos de los fármacos,
Indometacina,
Luteolina/farmacología,
Malondialdehído/análisis,
Metanol/farmacología,
Extractos Vegetales/farmacología,
Ratas Wistar,
Reproducibilidad de los Resultados,
Índice de Severidad de la Enfermedad,
Úlcera Gástrica/tratamiento farmacológico,
Úlcera Gástrica/patología,
Superóxido Dismutasa/análisis,
Superóxido Dismutasa/efectos de los fármacos,
Resultado del Tratamiento,
Asphodelaceae/química
ABSTRACT BACKGROUND Leathery Murdah, Terminalia coriacea (Roxb.) Wight & Arn. from family Combretaceae is used in Ayurveda and Siddha traditional systems of medicine to heal ulcers. OBJECTIVE The present study was conducted to assess the gastroprotective effect and understand the fundamental mecha...
Antiinflamatorios no Esteroideos,
Antiulcerosos/administración & dosificación,
Aspirina,
Modelos Animales de Enfermedad,
Relación Dosis-Respuesta a Droga,
Mucosa Gástrica/efectos de los fármacos,
Extractos Vegetales/administración & dosificación,
Ratas Wistar,
Úlcera Gástrica/inducido químicamente,
Úlcera Gástrica/tratamiento farmacológico,
Terminalia/química
Kalanchoe pinnata (Lam.) Pers. (Crassulaceae) é uma espécie muito empregada na medicina tradicional no Brasil e em outras partes do mundo, especialmente Índia, países da África e China. É indicada popularmente para diversos fins incluindo o tratamento de úlceras gástricas. A análise fitoquímica...
ABSTRACT PURPOSE: To evaluate the role of low molecular chitosan containing sepia ink (LMCS) in ethanol-induced (5 ml/kg) gastric ulcer in rats. METHODS: Animals were divided into four groups (n = 12): normal group (Normal), negative control group (Con), experiment group (LMCS) and positive control Om...
Antiulcerosos/uso terapéutico,
Antioxidantes/farmacología,
Quitosano/uso terapéutico,
Mucosa Gástrica/efectos de los fármacos,
Sepia/química,
Úlcera Gástrica/tratamiento farmacológico,
Antioxidantes/metabolismo,
Quitosano/química,
Modelos Animales de Enfermedad,
Etanol,
Mucosa Gástrica/patología,
Hidroxiprolina/metabolismo,
Tinta,
Malondialdehído/metabolismo,
Peso Molecular,
Distribución Aleatoria,
Úlcera Gástrica/inducido químicamente
