SUMMARY: The study explores the relationship between chronic exposure to fine particulate matter (PM2.5), sourced from wood smoke, and the histological structure and endocrine function of the uterus in nulliparous adult rats. It assesses potential structural changes in the uterus that could impact reprod...
An alternative hyper-ovulator inducer to replace clomiphene citrate (CC) is needed as it is unsuitable for women with polycystic ovarian syndrome and is associated with low pregnancy rates. Anastrozole is an effective hyper-ovulator inducer, but has not been well researched. In order to determine the eff...
Abstract Objective To assess the efficacy of non-surgical treatment for adenomyosis. Data Sources A search was performed by two authors in the Pubmed, Scopus, and Scielo databases and in the grey literature from inception to March 2018, with no language restriction. Selection of Studies We have inclu...
Abstract This study aimed to carry out an ethnobotanical survey of medicinal plants used by inhabitants of the Rodeadouro Island, Jatoba Island and Massangano Island, located in The Submedium São Francisco River Valley. Also phytochemicals and preliminary pharmacological tests were performed to species...
Abstract Purpose: To investigate the effect of melatonin on uterine tissue in the ovariectomized rat model. Methods: Fourty Wistar albino rats were divided into four groups for histologic and immunohistochemical examination. The rats were first numbered randomly and then randomly divided into 4 equal...
Actinas/análisis,
Antioxidantes/farmacología,
Western Blotting,
Estro/efectos de los fármacos,
Genes bcl-2/efectos de los fármacos,
Inmunohistoquímica,
Malondialdehído/análisis,
Melatonina/farmacología,
Ovariectomía,
Distribución Aleatoria,
Útero/efectos de los fármacos,
Útero/patología,
Factor A de Crecimiento Endotelial Vascular/análisis,
Factor A de Crecimiento Endotelial Vascular/efectos de los fármacos
Previous studies have shown that air pollution affects cardio-respiratory function, but its role regarding reproductive processes is unknown. There are few experimental background studies on its effects on the morpho-function in the reproductive system. The use of wood combustion for residential heating ...
Abstract Purpose: To evaluate the impact of systemic cyclophosphamide treatment on the rat uterus and investigate the potential therapeutic effects of natural antioxidant preparations curcumin and capsaicin against cyclophosphamide side effects. Methods: A 40 healthy adult female Wistar albino rats w...
Antineoplásicos Alquilantes/efectos adversos,
Antioxidantes/farmacología,
Capsaicina/farmacología,
Catalasa/análisis,
Curcumina/farmacología,
Ciclofosfamida/efectos adversos,
Glutatión/análisis,
Glutatión Peroxidasa/análisis,
Malondialdehído/análisis,
Estrés Oxidativo/efectos de los fármacos,
Distribución Aleatoria,
Ratas Wistar,
Reproducibilidad de los Resultados,
Superóxido Dismutasa/análisis,
Enfermedades Uterinas/inducido químicamente,
Enfermedades Uterinas/prevención & control,
Útero/efectos de los fármacos,
Útero/patología
SUMMARY: An alternative superovulator to replace clomiphene citrate is needed as clomiphene citrate is associated with low pregnancy rates. Anastrozole is an effective superovulator, but it has not been well researched. In order to determine the effectiveness of anastrozole as a superovulator and to comp...
Nitrilos/farmacología,
Triazoles/farmacología,
Vinculina/efectos de los fármacos,
Integrinas/efectos de los fármacos,
Adhesiones Focales/efectos de los fármacos,
Microscopía Confocal,
Microscopía Fluorescente,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Útero/efectos de los fármacos,
Células Epiteliales/efectos de los fármacos,
Vinculina/fisiología,
Vinculina/genética,
Integrinas/fisiología,
Integrinas/genética,
Ratas Wistar
Arthritis is positively associated with the decline of sex hormones, especially estrogen. Tamoxifen (TMX) is a selective estrogen receptor modulator, possessing agonist or antagonistic activity in different tissues. Thus, the objective of this study was to investigate the effect of TMX on the zymosan-ind...
Artritis Experimental/tratamiento farmacológico,
Ensayos de Migración de Leucocitos,
Movimiento Celular/efectos de los fármacos,
Modelos Animales de Enfermedad,
Antagonistas de Estrógenos/farmacología,
Ciclo Estral/efectos de los fármacos,
Neutrófilos/efectos de los fármacos,
Tamaño de los Órganos/efectos de los fármacos,
Ovariectomía,
Moduladores Selectivos de los Receptores de Estrógeno/farmacología,
Tamoxifeno/farmacología,
Factores de Tiempo,
Resultado del Tratamiento,
Útero/efectos de los fármacos,
Zimosan
Collagen is the most abundant structural protein found in organs and is responsible for providing tissues with structure and function. In order to investigate in canine uteri the potential effect of medroxyprogesterone acetate (MPA) on the changes in collagen deposition were grouped as nulliparous (n=11)...
