The effect of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) on mice myocardial morphology
Pesqui. vet. bras; 39 (5), 2019
Studies have demonstrated sympathetic cardiac denervation in the MPTP mouse model. MPTP toxicity causes sympathetic nerve damage and depletion of heart norepinephrine. Previous evaluations of impairments in heart innervation have been based on imaging, electrophysiological and biochemical methods. Howeve...