Domestic donkey plays a key role as a draft animal in rural economy of Pakistan where its population is increasing every year. The complete mtDNA control region of forty randomly sampled donkeys was PCR- amplified and sequenced bi-directionally using specific primers. Distinct mtDNA haplotypes obtained i...
BACKGROUND: Retinal neurodegeneration is induced by a variety of environmental insults and stresses, but the exact mechanisms are unclear. In the present study, we explored the involvement of cytosolic mitochondrial DNA (mtDNA), resulting in the cGAS-STING dependent inflammatory response and apoptosis in...
Karamat, Sana;
Ashraf, Nasra;
Akhtar, Tasleem;
Rahim, Faisal;
Shafi, Nuzhat;
Khalid, Saba;
Shahid, Benish;
Khawaja, Sundas;
Rahim, Junaid;
Majeed, Zahid;
Lateef, Zahid;
Mehmood, Majid.
Abstract The flying fox (Pteropus giganteus) also familiar with the name of the greater Indian fruit Bat belongs to the order Chiroptera and family Pteropodidae. Current research emphasis on the DNA barcoding of P. giganteus in Azad Jammu Kashmir. Bat sequences were amplified and PCR products were sequen...
Gymnogeophagus labiatus and G. lacustris have been long recognized as sister species exhibiting different ecological requirements. Gymnogeophagus labiatus occurs in rock bottom rivers in the hydrographic basins of Patos Lagoon (HBP) and Tramandaí River (HBT), while G. lacustris is exclusive from sand bo...
Cruz, Vanessa P;
Adachi, Aisni M.C. L;
Oliveira, Pablo H;
Ribeiro, Giovana S;
Paim, Fabilene G;
Souza, Bruno C;
Rodrigues, Alexandre S. F;
Vianna, Marcelo;
Delpiani, Sergio M;
Díaz de Astarloa, Juan Martín;
Rotundo, Matheus M;
Mendonça, Fernando F;
Oliveira, Claudio;
Lessa, Rosangela P;
Foresti, Fausto.
The guitarfishes Pseudobatos horkelii and Pseudobatos percellens meet the criteria for threatened status as Critically Endangered (CR) and Endangered (EN), respectively. Both species occur in the Southern Atlantic Ocean. Considering the lack of data on the genetic structure of these species, the present ...
A Síndrome de Leigh (SL) é uma doença neuro-metabólica congênita, que faz parte do grupo das encefalopatias fatais, com progressão e morte dentro de 2 anos, em média. A SL é causada por mutações no DNA que causam alterações na geração de ATP celular pelas mitocôndrias. As mitocôndrias con...
Physical performance is a multifactorial and complex trait influenced by environmental and hereditary factors. Environmental factors alone have been insufficient to characterize all outstanding phenotypes. Recent advances in genomic technologies have enabled the investigation of whole nuclear and mitocho...
Abstract Background: Although not fully understood, oxidative stress has been implicated in the pathogenesis of different autoimmune diseases such as systemic sclerosis. Accumulating evidence indicates that oxidative stress can induce mitochondrial DNA (mtDNA) damage and variations in mtDNA copy number ...
Estudios de Casos y Controles,
Variaciones en el Número de Copia de ADN,
Daño del ADN,
ADN Mitocondrial/sangre,
ADN Mitocondrial/genética,
Electroforesis en Gel de Agar,
Persona de Mediana Edad,
Estrés Oxidativo/genética,
Especies Reactivas de Oxígeno/sangre,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Valores de Referencia,
Esclerodermia Sistémica/sangre,
Esclerodermia Sistémica/genética,
Estadísticas no Paramétricas
The ancient catfish family Diplomystidae, with seven species endemic to rivers of southern South America, represents one of the oldest branches of the diverse order Siluriformes. With most species endangered, new reports of these species become extremely valuable for conservation. Currently, it is assume...
Background: Snakes are found on every continent in the world except Antarctica, and on smaller land masses. Being ecologically important, they also cause a large number of bites, leading to millions of deaths. Mitochondrial and nuclear gene sequences are being used to identify, characterize, and infer ge...
