Glycoprotein nonmetastatic melanoma protein B accelerates tumorigenesis of cervical cancer in vitro by regulating the Wnt/β-catenin pathway
Braz. j. med. biol. res; 52 (1), 2019
Cervical cancer is one of the most common cancers among women around the world. However, the underlying mechanism involved in cervical cancer progression is incompletely known. In the present study, we determined the role of glycoprotein nonmetastatic melanoma protein B (GPNMB) in tumorigenesis of cervic...
Apoptosis, Western Blotting, Línea Celular Tumoral, Movimiento Celular, Proliferación Celular, Regulación Neoplásica de la Expresión Génica/genética, Metaloproteinasa 2 de la Matriz/metabolismo, Metaloproteinasa 9 de la Matriz/metabolismo, Glicoproteínas de Membrana/genética, Glicoproteínas de Membrana/metabolismo, ARN Interferente Pequeño/metabolismo, Neoplasias del Cuello Uterino/genética, Neoplasias del Cuello Uterino/metabolismo, Neoplasias del Cuello Uterino/patología, Vía de Señalización Wnt/genética, beta Catenina/genética, beta Catenina/metabolismo