Possible senescence associated change in the predominant &alpha -Na+/K+ ATP-ase isoform in the renal cortex of the rat
Medicina (B.Aires); 76 (4), 2016
With aging the kidney exhibits progressive deterioration, with a decrease in renal function. Most of the filtered Na+ is actively reabsorbed in the proximal tubules through different transporters located in apical membrane. This process is possible because basolateral Na+/K+-ATP-ase generates electrochem...
Envejecimiento/metabolismo, Secuencia de Bases, Corteza Renal/enzimología, Médula Renal/enzimología, ARN Mensajero/análisis, ARN Mensajero/metabolismo, Distribución Aleatoria, Ratas Wistar, Sodio/metabolismo, ATPasa Intercambiadora de Sodio-Potasio/análisis, ATPasa Intercambiadora de Sodio-Potasio/genética, ATPasa Intercambiadora de Sodio-Potasio/metabolismo