Abstract Objective To assess the prevalence and type of chromosomal abnormalities in Brazilian couples with recurrent pregnancy loss (RPL) and compare the clinical characteristics of couples with and without chromosome abnormalities. Methods We assessed the medical records of 127 couples with a histo...
Kuspanova, Meruyet;
Gaiday, Andrey;
Dzhardemaliyeva, Nurzhamal;
Tuganbayev, Maxat;
Gorobeiko, Maksym;
Dinets, Andrii;
Bermagambetova, Saule;
Amirbekova, Zhanna;
Oraltayeva, Gulshat;
Omertayeva, Dinara;
Tussupkaliyev, Akylbek.
Abstract Objective 26% of all pregnancies end in miscarriage, and up to 10% of clinically diagnosed pregnancies, and recurrent pregnancy loss is 5% among couples of childbearing ages. Although there are several known causes of pregnancy loss in the first half, including recurrent pregnancy loss, includ...
Abstract For many centuries human populations have been suffering and trying to fight with disease-bearing mosquitoes. Emerging and reemerging diseases such as Dengue, Zika, and Chikungunya affect billions of people around the world and recently has been appealing to control with chemical pesticides. Mal...
Awan, U A;
Farooq, N;
Sarwar, A;
Jehangir, H M S;
Hashmi, M S;
Alamgir, M;
Waheed, F;
Khurram, M;
Ahmed, H;
Khattak, A A;
Afzal, M S.
Abstract Hematological and hematopoietic cells malignancies of the genes and hematopoietic cells are associated with the genetic mutation, often at the chromosomal level. The standard cytogenetic study is widely accepted as one of the main diagnostics and prognostic determinants in patients. Therefore, t...
Cavalcanti, Bruno Coêlho;
Silva, Cecília Rocha da;
Andrade Neto, João Batista de;
Josino, Maria Aparecida Alexandre;
Sá, Lívia Gurgel do Amaral Valente;
Silva, Antônio Adailson de Sousa;
Barreto, Francisco Stefânio;
Ferreira, José Roberto de Oliveira;
Magalhães, Hemerson Iury Ferreira;
Vieira, Ícaro Gusmão Pinto;
Brito, Débora Hellen Almeida;
Ricardo, Nágila Maria Pontes Silva;
Barroso, Fátima Daiana Dias;
Costa, Érica Rayanne Mota da;
Nobre Júnior, Hélio Vitoriano;
Moraes, Manoel Odorico de.
Objectives: The purpose of this study was to evaluate the mutagenic potential of fluoxetine and fluoxetine-galactomannan. Methods: Chromosomal aberration test and Salmonella typhimurium/microsome mutagenicity assay. Results: The results showed that fluoxetine (250 μg/mL) can cause chromosomal breaks of ...
Abstract Objective This study aims to describe the behavior of chromosomopathy screenings in euploid fetuses. Methods This is a prospective descriptive study with 566 patients at 11 to 14 weeks of gestation. The associations between ultrasound scans and serological variables were studied. For the quant...
Resumen La prevalencia mundial de la discapacidad intelectual (DI) es del 3 %. Una de las causas más comunes de DI de origen genético son las aberraciones cromosómicas, las cuales resultan fácilmente detectables mediante un cariotipo. Sin embargo, muchas de estas pasan desapercibidas durante el anál...
INTRODUCCIÓN: La infertilidad es una enfermedad multicausal y el componente genético representa uno de sus principales eventos. Si bien la distribución de la infertilidad puede variar entre poblaciones, las parejas de los países con bajos y medianos ingresos pueden verse más afectadas por la inferti...
Viñals, Fernando;
Selman, Eliana;
Guajardo, Hugo;
Koenig, Katrin;
Quiroz, Gabriel;
Hormazábal, Lorena;
Zambrano, Belkys;
Saint-Jean, Constanza;
Díaz, Linder;
Vergara, Paula.
OBJETIVO: Analizar la implementación de la prueba rápida de reacción en cadena de la polimerasa cuantitativa y fluorescente (QF-PCR) para la detección de aneuploidías. MÉTODO: Se incluyeron todas las pacientes que se realizaron una QF-PCR entre septiembre de 2017 y mayo de 2021. En todos los casos ...
A maioria dos casos de portadores de translocações balanceadas são clinicamente normais, porém, cerca de 7% delas estão associadas a alterações fenotípicas, que incluem malformações congênitas e/ou retardo mental. Investigações detalhadas das regiões dos sítios de quebra desses rearranjos ...
