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Comparative study of sustained-release lipid microparticles and solid dispersions containing ibuprofen

Braz. j. pharm. sci; 48 (3), 2012
Ibuprofen is one of the most important non-steroidal anti-inflammatory drugs used in the treatment of inflammatory diseases. In its pure state, ibuprofen presents poor physical and mechanical characteristics and its use in solid dosage forms needs the addition of excipients that improve these properties....