LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Optimization of cosmetic formulations development using Box-Behnken design with response surface methodology: physical, sensory and moisturizing properties

Mercurio, Daiane Garcia; Calixto, Lívia Salomão; Campos, Patrícia Maria Berardo Gonçalves Maia.

Braz. J. Pharm. Sci. (Online); 56 (), 2020

Considering the importance of an adequate composition of the formulation in the development of stable, safe and effective cosmetic products, experimental design techniques are tools that can optimize the formulation development process. The objective of this study was to develop topical formulations usin...

Optimización de Procesos/métodos, Tecnología de Cosméticos, Emulsiones/análisis, Resultado del Tratamiento, Ácidos/administración & dosificación, Piel, Proyectos de Investigación, Métodos, Cosméticos/análisis, Acrilatos/efectos adversos, Química Farmacéutica/instrumentación, Estabilidad de Cosméticos

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Idiosyncratic reaction after injection of polyacrylate - polyalcohol copolymer

ABSTRACT Context: Polyacrylate-polyalcohol copolymer is a synthetic product, non-biodegradable, with low rate of therapeutic failure and lower incidence of reactions at the site of injection, when compared to biodegradable agents. We report an unprecedent, exuberant and persistent inflammatory reaction ...