Abstract Ananas Comosus (also known as pineapple) is a part of Bromeliaceae family and it is consumed as food as well as folk medicine for the treatment of various diseases. It is reported that pineapple is a rich source of bromelain, a cysteine protease and it is considered as an important enzyme in dif...
Abstract The evolution of species is inevitably accompanied by the evolution of metabolic networks to adapt to different environments. The metabolic networks of different species were collected from the Kyoto Encyclopedia of Genes and Genomes (KEGG) website, and some enzyme reactions with the highest occ...
Abstract The unconscious use of pesticides causes various adverse effects on non-target organisms, including humans. Enzymes that control metabolism become the target of the pesticide and the organs are damaged due to toxic effects. Glutathione s-transferase (GST, EC 2.5.1.18), an important enzyme of the...
Abstract Endophytic fungi belonging to the genus Muscodor now transferred to Induratia are known producers of bioactive volatile organic compounds (VOCs) with many industrial applications. However, the members of this genus have rarely been reported to produce non-volatile metabolites including enzyme. E...
Lima, Hélimar Gonçalves de;
Santos, Francianne Oliveira;
Santos, Acidália Carine Vieira;
Silva, Gisele Dias da;
Santos, Rafaela Jesus dos;
Carneiro, Kelli de Oliveira;
Reis, Isabella Mary Alves;
Estrela, Isabela de Oliveira;
Freitas, Humberto Fonseca de;
Bahiense, Thiago Campanharo;
Pita, Samuel Silva da Rocha;
Uzeda, Rosângela Soares;
Branco, Alexsandro;
Costa, Silvia Lima;
Batatinha, Maria José Moreira;
Botura, Mariana Borges.
Abstract We investigated the in vitro acaricide activity of the methanolic extract (ME) and alkaloid-rich fraction (AF) of Prosopis juliflora on Rhipicephalus microplus and correlated this effect with acetylcholinesterase (AChE) inhibition. The acaricide activity was evaluated using adult and larval imme...
Acaricidas/farmacología,
Alcaloides/farmacología,
Colinesterasas/metabolismo,
Cromatografía Liquida,
Activación Enzimática/efectos de los fármacos,
Larva,
Simulación del Acoplamiento Molecular,
Extractos Vegetales/farmacología,
Prosopis/química,
Rhipicephalus/efectos de los fármacos,
Rhipicephalus/enzimología,
Espectrometría de Masas en Tándem
Resumen: Los desórdenes congénitos de glicosilación son un conjunto de defectos genéticos de tipo multisistémico que afectan la función de la proteína. Se han descrito cerca de 75 enfermedades desde sus primeros estudios. En el presente estudio se desarrolló un método microespectrofotométrico p...
Wolf cichlid, Parachromis dovii, is a species with a high potential for aquaculture in Central America; however, the knowledge of the digestive physiology in larvae period is limited. For these reason, this study evaluated the changes on digestive enzymes (alkaline and acid proteases, trypsin, chymotryps...
Abstract Purpose: To investigate the effect of alprostadil on myocardial ischemia/reperfusion (I/R) in rats. Methods: Rats were subjected to myocardial ischemia for 30 min followed by 24h reperfusion. Alprostadil (4 or 8 μg/kg) was intravenously administered at the time of reperfusion and myocar...
Alprostadil/farmacología,
Antioxidantes/farmacología,
Western Blotting,
Catalasa/análisis,
Forma MB de la Creatina-Quinasa/sangre,
Forma MB de la Creatina-Quinasa/efectos de los fármacos,
Activación Enzimática/efectos de los fármacos,
Ventrículos Cardíacos/efectos de los fármacos,
Ventrículos Cardíacos/patología,
L-Lactato Deshidrogenasa/sangre,
L-Lactato Deshidrogenasa/efectos de los fármacos,
Malondialdehído/análisis,
Infarto del Miocardio/patología,
Daño por Reperfusión Miocárdica/metabolismo,
Daño por Reperfusión Miocárdica/patología,
Daño por Reperfusión Miocárdica/prevención & control,
Óxido Nítrico/análisis,
Óxido Nítrico Sintasa de Tipo III/metabolismo,
Estrés Oxidativo/efectos de los fármacos,
Distribución Aleatoria,
Ratas Sprague-Dawley,
Reproducibilidad de los Resultados,
Superóxido Dismutasa/análisis,
Resultado del Tratamiento,
Troponina T/sangre,
Troponina T/efectos de los fármacos
ABSTRACT The aim of this study was to optimize the dextranase production by fungus Pochonia chlamydosporia (VC4) and evaluate its activity in dextran reduction in sugarcane juice. The effects, over the P. chlamydosporia dextranase production, of different components from the culture medium were analyzed ...
Fraccionamiento Químico/métodos,
Medios de Cultivo/metabolismo,
Dextranasa/biosíntesis,
Dextranos/metabolismo,
Electroforesis en Gel de Poliacrilamida,
Activación Enzimática,
Jugos de Frutas y Vegetales/análisis,
Concentración de Iones de Hidrógeno,
Hypocreales/enzimología,
Modelos Estadísticos,
Nitratos,
Saccharum/metabolismo,
Temperatura
Abstract Purpose: To investigate whether modulating GSK-3β could attenuate myocardial ischemia reperfusion injury (MIRI) induced acute lung injury (ALI) and analyze the underlying mechanism. Methods: Male SD rats were subjected to MIRI with or without myocardial ischemic post-conditioning in the...
Lesión Pulmonar Aguda/prevención & control,
Glucógeno Sintasa Quinasa 3 beta/metabolismo,
Poscondicionamiento Isquémico/métodos,
Daño por Reperfusión Miocárdica/prevención & control,
Sustancias Protectoras/metabolismo,
Lesión Pulmonar Aguda/enzimología,
Apoptosis/efectos de los fármacos,
Caspasa 3/metabolismo,
Regulación hacia Abajo,
Activación Enzimática,
Glucógeno Sintasa Quinasa 3 beta/antagonistas & inhibidores,
Glucógeno Sintasa Quinasa 3 beta/farmacología,
Etiquetado Corte-Fin in Situ,
Inflamación/metabolismo,
Interleucinas/metabolismo,
Modelos Animales,
Infarto del Miocardio/patología,
Neutrófilos/enzimología,
Peroxidasa/metabolismo,
Sustancias Protectoras/farmacología,
Proteínas Proto-Oncogénicas c-bcl-2/metabolismo,
Distribución Aleatoria,
Ratas Sprague-Dawley,
Proteína X Asociada a bcl-2/metabolismo
