Results: 9

Sistema glinfático: aspectos anatómicos, fisiológicos e implicaciones clínicas
Glymphatic system: Anatomo-physiological principles and their clinical implications

Acta neurol. colomb; 39 (2), 2023
Introducción: El sistema glinfático comprende el conjunto de rutas perivasculares tanto arteriales como venosas que se encuentran en estrecha asociación con células astrogliales y que permiten la interacción entre el líquido cefalorraquídeo (LCR) y el líquido intersticial cerebral (LIC), para lle...

Long-term safety of azathioprine for treatment of neuromyelitis optica spectrum disorders

Arq. neuropsiquiatr; 79 (3), 2021
ABSTRACT Background: Azathioprine is a common first-line therapy for neuromyelitis optica spectrum disorder (NMOSD). Objective: The aim of this study was to determine whether long-term treatment (>10 years) with azathioprine is safe in NMOSD. Methods: We conducted a retrospective medical record re...

Different expressions of AQP1 and AQP4 in hyponatremic rat brain

Int. j. morphol; 39 (1), 2021
SUMMARY: The expression of aquaporin-1 (AQP1) in choroid plexus and aquaporin-4 (AQP4) in astrocyte of the hippocampal formation (HF) was studied in the rat to determine the role of AQP1 and AQP4 in the pathophysiology of systemic hyponatremia (SH). SH was induced by coadministration of dextrose solution...

Mielitis longitudinal extensa de presentación muy tardía: Una entidad del espectro de la neuromielitis óptica
Extensive longitudinal myelitis of very late presentation. An entity of the spectrum of optic neuromyelitis

Medicina (B.Aires); 80 (3), 2020
Las enfermedades del espectro neuromielitis óptica son trastornos inflamatorios del sistema nervioso central caracterizados por una grave desmielinización y daño axonal inmunomediado que afecta principalmente a los nervios ópticos y médula espinal. Suelen presentars e en edades tempranas, aunque exi...

Enfermedades desmielinizantes
Demyelinating disorders

Medicina (B.Aires); 78 (supl.2), 2018
Las enfermedades desmielinizantes constituyen un grupo de afecciones de etiología autoinmune dirigida contra la mielina del sistema nervioso central. En muchos casos, el inicio del cuadro es precedido por una infección viral inespecífica. La esclerosis múltiple evoluciona con recaídas y remisiones c...

Effects of aquaporin 4 and inward rectifier potassium channel 4 1 on medullospinal edema after methylprednisolone treatment to suppress acute spinal cord injury in rat

Acta cir. bras; 33 (2), 2018
Abstract Purpose: To investigate the effects of aquaporin 4 (AQP4) and inward rectifier potassium channel 4.1 (Kir4.1) on medullospinal edema after treatment with methylprednisolone (MP) to suppress acute spinal cord injury (ASCI) in rats. Methods: Sprague Dawley rats were randomly divided into contro...

Extremely dilution of strychnos Nux vomica mitigates alcohol-induced reduction in enthalpies associated with free water molecules in a fish brain

Int. j. high dilution res; 17 (3/4), 2018
Introduction: Alcohol intoxication affects aquaporins in the glial cells of brain resulting in oedema. Nux vomica, a homeopathic drug of plant origin, is known to counteract alcohol effect. The objective of this present study is to find out the level of free water molecules in the brain of a teleost fish...

Neuromyelitis optica: phenotypic characteristics in a Brazilian case series

Arq. neuropsiquiatr; 75 (2), 2017
ABSTRACT The definition of neuromyelitis optica (NMO) is still evolving. In 2015, the International Panel for NMO Diagnosis was convened to develop revised diagnostic criteria. There have been few studies on NMO in the Brazilian population. Objective To describe the characteristics of 34 Brazilian NMO ...

Validez diagnóstica de la detección de anticuerpos anti-acuaporina 4 (AQP4) para el diagnóstico clínico de neuromielitis óptica (NMO)
Diagnostic validity of the detection of anti-aquaporin 4 antibodies (AQP4) for the clinical diagnosis of optic neuromyelitis (NMO)

Introducción: La neuromielitis óptica (NMO) es un trastorno autoinmune inflamatorio del sistema nervioso central (SNC) que hasta hace poco se consideraba parte del espectro de la esclerosis múltiple (EM). Sinembargo, desde la identificación del anticuerpo anti-NMO se diferenció de otras enfermedades...