Pavón, Alequis;
Corsini, Gino;
Orellana, Paz;
Calisto, Nancy;
Navarro, Laura;
Wiese, Guillermo;
Cortés-Cortés, Piedad;
Gidekel, Manuel;
Gutierrez-Moraga, Ana;
Salazar, Lorena.
SUMMARY: Cancer is the second leading cause of death in the world and colorectal cancer is the only cancer that has shown a sustained increase in mortality in the last decade. In the search for new chemotherapeutic agents against cancer, extremophilic microorganisms have shown to be a potential source to...
Microbiología del Suelo,
Regiones Antárticas,
Bacillus/fisiología,
Bacillus/aislamiento & purificación,
Bacillus/genética,
Proliferación Celular/efectos de los fármacos,
Neoplasias Colorrectales/tratamiento farmacológico,
Línea Celular Tumoral/efectos de los fármacos,
Supervivencia Celular/efectos de los fármacos,
ARN Ribosómico 16S,
Fenotipo,
Genotipo,
Técnicas In Vitro,
Adenocarcinoma/tratamiento farmacológico,
Reacción en Cadena de la Polimerasa
ABSTRACT The concomitant epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) translocations in lung adenocancers are very rare scenarios. Until now, 42 cases described in the literature have all been treated by different drugs. There is no overall consensus regarding the...
Adenocarcinoma/genética,
Neoplasias Pulmonares/genética,
Mutación/genética,
Genes erbB-1/genética,
Exones/genética,
Crizotinib/uso terapéutico,
Inhibidores de Proteínas Quinasas/uso terapéutico,
Docetaxel/uso terapéutico,
Cisplatino/uso terapéutico,
Antineoplásicos/uso terapéutico,
Neoplasias Pulmonares/tratamiento farmacológico,
Adenocarcinoma/tratamiento farmacológico
ABSTRACT Background: Gastric and esophagogastric junction adenocarcinoma are responsible for approximately 13.5% of cancer-related deaths. Given the fact that these tumors are not typically detected until they are already in the advanced stages, neoadjuvancy plays a fundamental role in improving long-t...
Adenocarcinoma/tratamiento farmacológico,
Adenocarcinoma/patología,
Adenocarcinoma/cirugía,
Protocolos de Quimioterapia Combinada Antineoplásica,
Endoscopía,
Unión Esofagogástrica,
Terapia Neoadyuvante,
Estadificación de Neoplasias,
Neoplasias Gástricas/tratamiento farmacológico,
Neoplasias Gástricas/patología,
Neoplasias Gástricas/cirugía,
Resultado del Tratamiento
Juniperus communis (JCo) is a well-known traditional Chinese medicinal plant that has been used to treat wounds, fever, swelling, and rheumatism. However, the mechanism underlying the anticancer effect of JCo extract on colorectal cancer (CRC) has not yet been elucidated. This study investigated the anti...
Adenocarcinoma/tratamiento farmacológico,
Antineoplásicos Fitogénicos/farmacología,
Apoptosis,
Ciclo Celular,
Puntos de Control del Ciclo Celular,
Línea Celular Tumoral,
Proliferación Celular,
Neoplasias Colorrectales/tratamiento farmacológico,
Juniperus,
Ratones Endogámicos BALB C,
Extractos Vegetales/farmacología
ABSTRACT Purpose Standard of care for locally advanced rectal cancer is neoadjuvant chemoradiotherapy followed by surgery. This study identified predictive factors for tumour response in our series. Patients and methods Between January 2005 and December 2018, 292 patients with locally advanced rectal c...
BackgroundBreast cancer has been considered a public health problem and homeopathic treatments are becoming increasingly recommended due to its ways of action and absence of adverse effects. MCF-7 is an adenocarcinoma of human breast cell line useful as preclinicalmodel to screen ther...
Neoplasias de la Mama/patología,
Terapéutica Homeopática,
Viscum album/toxicidad,
Técnicas de Cultivo de Célula,
Adenocarcinoma/patología,
Células MCF-7/efectos de los fármacos,
Células Madre Mesenquimatosas/efectos de los fármacos,
Neoplasias de la Mama/tratamiento farmacológico,
Adenocarcinoma/tratamiento farmacológico,
Recuento de Células,
Supervivencia Celular
Introduction: Three vanadium complexes with orotic and glutamic acids, in their anion forms, were prepared and their in vitro cytotoxicity toward human lung fibroblasts (MRC-5), human hepatocellular carcinoma (HepG2) and human colorectal adenocarcinoma (Caco-2) are reported. Objective: Describe the synth...
Carcinoma Hepatocelular/tratamiento farmacológico,
Compuestos de Vanadio/farmacología,
Ensayos de Selección de Medicamentos Antitumorales,
Técnicas In Vitro,
Ácido Orótico/farmacología,
Ácido Glutámico/farmacología,
Fibroblastos Asociados al Cáncer/efectos de los fármacos,
Neoplasias Pulmonares/tratamiento farmacológico,
Adenocarcinoma/tratamiento farmacológico,
Neoplasias Colorrectales/tratamiento farmacológico,
Antineoplásicos/farmacología,
Línea Celular Tumoral/efectos de los fármacos
Mammadov, Renad;
Suleyman, Bahadir;
Altuner, Durdu;
Demirci, Elif;
Cetin, Nihal;
Yilmaz, Adnan;
Baykal, Huseyin;
Alpcan, Hilal;
Turumtay, Emine Akyuz;
Suleyman, Halis.
Abstract Purpose: To investigate the effects of the EtOAc extract of U. longissima which is uninvestigated previously on esophagogastric cancer induced in rats with N-methyl-N-nitro-N-nitrosoguanidin (MNNG). Methods: The anticancer activity of EtOAc extract of U. longissima was examined in the esopha...
RESUMO Objetivo: analisar a expressão do Fator de Crescimento do Endotélio Vascular (VEGF), seu receptor (VEGFR-2), idade e tipo histológico de carcinomas avançados de colo uterino com relação à resposta clínica à quimioterapia neoadjuvante. Métodos: foram incluídas 40 pacientes com diagnós...
Adenocarcinoma/tratamiento farmacológico,
Adenocarcinoma/cirugía,
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico,
Biopsia,
Carcinoma Adenoescamoso/tratamiento farmacológico,
Carcinoma Adenoescamoso/patología,
Carcinoma Adenoescamoso/cirugía,
Carcinoma de Células Escamosas/tratamiento farmacológico,
Carcinoma de Células Escamosas/patología,
Carcinoma de Células Escamosas/cirugía,
Cuello del Útero,
Cisplatino,
Persona de Mediana Edad,
Terapia Neoadyuvante,
Estadificación de Neoplasias,
Estudios Prospectivos,
Neoplasias del Cuello Uterino/tratamiento farmacológico,
Neoplasias del Cuello Uterino/patología,
Neoplasias del Cuello Uterino/cirugía,
Receptor 2 de Factores de Crecimiento Endotelial Vascular/uso terapéutico
