Results: 5

Proteína moduladora de la actividad del receptor de aril hidrocarburos (AIP): genética, bioquímica e impacto clínico

Repert. med. cir; 30 (1), 2021
El gen AIP (proteína moduladora de la actividad del receptor de aril hidrocarburos) se localiza en la región 11q13.2 y codifica para una proteína de 330 aminoácidos que interactúa con el factor de transcripción AhR (receptor para aril hidrocarburos). Las muta...

Effect of lncRNA HULC knockdown on rat secreting pituitary adenoma GH3 cells

Braz. j. med. biol. res; 52 (4), 2019
Pituitary adenoma is one of the most common tumors in the neuroendocrine system. This study investigated the effects of long non-coding RNAs (lncRNAs) highly up-regulated in liver cancer (HULC) on rat secreting pituitary adenoma GH3 cell viability, migration, invasion, apoptosis, and hormone secretion, a...

Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report

Clinics; 72 (4), 2017
OBJECTIVE: To evaluate the effectiveness of the treatment of acromegaly patients at the Federal University of Triangulo Mineiro. METHODS: Cross-sectional and retrospective study of thirty cases treated over a period of two decades. RESULTS: 17 men (56.7%) aged 14-67 years and 13 women aged 14-86 years ...

Benchmarking pathway interaction network for colorectal cancer to identify dysregulated pathways

Braz. j. med. biol. res; 50 (5), 2017
Different pathways act synergistically to participate in many biological processes. Thus, the purpose of our study was to extract dysregulated pathways to investigate the pathogenesis of colorectal cancer (CRC) based on the functional dependency among pathways. Protein-protein interaction (PPI) informati...

The destruction complex of beta-catenin in colorectal carcinoma and colonic adenoma

Einstein (Säo Paulo); 14 (2), 2016
ABSTRACT Objective To evaluate the destruction complex of beta-catenin by the expression of the proteins beta-catetenin, adenomatous polyposis coli, GSK3β, axin and ubiquitin in colorectal carcinoma and colonic adenoma. Methods Tissue samples from 64 patients with colorectal carcinoma and 53 pat...