Results: 15

Influencia de la seropositividad contra adenovirus-36 sobre riesgo de obesidad y resistencia a la insulina en población infanto-juvenil de la Región de la Araucanía

La infección previa por el adenovirus-36 (Ad-36) se ha asociado con el proceso adipogénico y el control glicémico en modelos experimentales de cultivos celulares y animales. En humanos, la presencia de anticuerpos contra Ad-36 ha mostrado aumentar el riesgo de obesidad y, paradójicamente, mejorar el ...

Terapia genética de injeção intravítrea de rAAV2-ND4 para neuropatia óptica hereditária de Leber: uma revisão sistemática

Rev. bras. oftalmol; 82 (), 2023
RESUMO A neuropatia óptica hereditária de Leber é uma doença mitocondrial hereditária neurodegenerativa. A taxa potencial de recuperação espontânea é controversa na literatura. A terapia genética tem sido estudada como suporte aos pacientes. O objetivo desta revisão foi avaliar qualitativament...

Hepatitis de etiología no precisada en población pediátrica

Rev. chil. infectol; 39 (4), 2022
Resumen En los últimos meses, se ha comunicado globalmente, un aumento de casos de hepatitis de etiología no precisada. La población más afectada son los niños bajo los 5 años, pero con un rango etario hasta los 16 años. Clínicamente, se presentan con una hepatitis colestásica con pródromos de ...

Adenovirus 36 infection and daycare starting age are associated with adiposity in children and adolescents

J. pediatr. (Rio J.); 97 (4), 2021
Abstract Objective This study aimed to investigate human adenovirus 36 (Adv36) as an associated factor for adiposity in children and adolescents aged 9-12 years. Methods This was a case-control study comparing overweight (cases) and eutrophic (controls) children and adolescents aged 9-12 years based on...

Interpretación de biomarcadores en pacientes pediátricos con infección por Adenovirus

Metro cienc; 28 (4), 2020
RESUMEN Objetivo: Evaluar el uso de los biomarcadores proteína C reactiva (PCR) y procalcitonina (PCT) para la valoración de severidad clínica en pacientes pediá-tricos diagnosticados con infección por adenovirus. Método: Se estudiaron 100 pacientes mayores de 28 días y menores a 15 años con diag...

More than just a common cold: endemic coronaviruses OC43, HKU1, NL63, and 229E associated with severe acute respiratory infection and fatality cases among healthy adults

J. med. virol; 92 (10), 2020
Respiratory viral infection can cause severe disease and hospitalization, especially among children, the elderly, and patients with comorbidities. In Brazil, the official surveillance system of severe acute respiratory infection (SARI) investigates influenza A (IAV) and B (IBV) viruses, respiratory syncy...

The grim reaper evading modern medicine: aspergillosis, adenovirus, and Hodgkin lymphoma

Autops. Case Rep; 10 (4), 2020
Illustrative cases of diseases that are difficult to suspect and diagnose can serve as useful reminders. Invasive pulmonary aspergillosis and adenovirus hepatitis are two such diseases, both revealed by autopsy in this case of Hodgkin lymphoma refractory to chemotherapy treated with allogeneic hematopoie...

Management of acute respiratory distress syndrome in a child with adenovirus pneumonia: case report and literature review

ABSTRACT Objective: To report the case of a child who developed acute respiratory distress syndrome (ARDS) from a pulmonary infection by adenovirus. Case description: A female patient aged 2 years and 6 months, weighting 10,295 grams developed fever, productive cough and vomiting, later on progressin...

Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus: report of one case

Rev. méd. Chile; 147 (2), 2019
ABSTRACT Adenovirus (ADV) is a recognized cause of severe disease among immunocompromised patients. We report a previously healthy 39-year-old female, admitted with influenza pneumonia and evolving with lung hemorrhage and acute renal failure requiring mechanical ventilation and hemodialysis. She receive...

Improving adenoviral vectors and strategies for prostate cancer gene therapy

Clinics; 73 (supl.1), 2018
Gene therapy has been evaluated for the treatment of prostate cancer and includes the application of adenoviral vectors encoding a suicide gene or oncolytic adenoviruses that may be armed with a functional transgene. In parallel, versions of adenoviral vector expressing the p53 gene (Ad-p53) have been te...