LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Parenteral adjuvant potential of recombinant B subunit of Escherichia coli heat-labile enterotoxin

Cunha, Carlos Eduardo Pouey da; Moreira Junior, Clóvis; Rocha, Andréa da Silva Ramos; Finger, Paula Fonseca; Magalhães, Carolina Georg; Ferreira, Marcos Roberto Alves; Dellagostin, Odir Antônio; Moreira, Ângela Nunes; Conceição, Fabricio Rochedo.

Mem. Inst. Oswaldo Cruz; 112 (12), 2017

BACKGROUND The B subunit of Escherichia coli heat-labile enterotoxin (LTB) is a potent mucosal immune adjuvant. However, there is little information about LTB's potential as a parenteral adjuvant. OBJECTIVES We aimed at evaluating and better understanding rLTB's potential as a parenteral adjuvant using ...

Adhesinas Bacterianas/inmunología, Adyuvantes Inmunológicos/administración & dosificación, Hidróxido de Aluminio, Toxinas Bacterianas/toxicidad, Enterotoxinas/administración & dosificación, Ensayo de Inmunoadsorción Enzimática, Proteínas de Escherichia coli/administración & dosificación, Proteínas de Escherichia coli/inmunología, Mycoplasma hyopneumoniae, Neumonía Porcina por Mycoplasma/inmunología, Neumonía Porcina por Mycoplasma/prevención & control, Porcinos

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Placental and colostral transfer of antibodies reactive with enteropathogenic Escherichia coli intimins α, β, or γ

Abstract Objective: Intimins are protein adhesins of enteropathogenic Escherichia coli and enterohemorrhagic E. coli capable of inducing attachment and effacement lesions in enterocytes. Anti-intimin antibodies are important for the protection from enteropathogenic E. coli and enterohemorrhagic E. coli ...