Results: 10

Identification of new human mesenchymal stem cell biomarker by aptamers

Stem cells are undifferentiated cells that can be distinguished from others by their ability to self-renew and to differentiate into new specific cell types. Mesenchymal stem cells (MSC) are adult stem cells that can be obtained from different sources, such as adipose tissue, bone marrow, dental pulp, an...

C/EBPb converts bovine fibroblasts to adipocytes without hormone cocktail induction

BACKGROUND: Adipogenesis and fibrogenesis can be considered as a competitive process in muscle, which may affect the intramuscular fat deposition. The CCAAT/enhancer-binding protein beta (C/EBPb) plays an important role in adipogenesis, which is well-characterized in mice, but little known in bovine so f...

Myostatin coordinating the proliferation and differentiation of adipose and skeletal muscle cells and energy metabolism balance based on gene chip technology

Rev. bras. med. esporte; 27 (spe2), 2021
ABSTRACT Myoblasts fuse into multinucleated muscle fibers to form and promote the growth of skeletal muscle. In order to analyze the role of myostatin (MSTN) in body fat, skeletal muscle cell proliferation and differentiation and energy metabolism, this study will use the antisense RNA technology of gene...

Regulation of adiposity by mTORC1

Einstein (Säo Paulo); 15 (4), 2017
ABSTRACT Obesity is characterized by an excessive increase in the adipose tissue mass, and is associated with higher incidence of several chronic metabolic diseases, such as type 2 diabetes. Therefore, its increasing prevalence is a public health concern, and it is important to better understand its etio...

Alteração do tecido conjuntivo orbitário após aplicação de bimatoprost: estudo experimental em ratos

Rev. bras. oftalmol; 75 (4), 2016
RESUMO O bimatoprost é utilizado comumente como a droga de primeira escolha no tratamento do glaucoma primário de ângulo aberto. Hiperemia conjuntival, crescimento dos cílios, enoftalmia, escurecimento cutâneo periocular, sulco palpebral profundo e prurido ocular têm sido relatados em pacientes que...

Potential role of marine algae extract on 3T3-L1 cell proliferation and differentiation: an in vitro approach

Biol. Res; 49 (), 2016
BACKGROUND: From ancient times, marine algae have emerged as alternative medicine and foods, contains the rich source of natural products like proteins, vitamins, and secondary metabolites, especially Chlorella vulgaris (C. vulgaris) contains numerous anti-inflammatory, antioxidants and wound healing sub...

Renin-angiotensin system blockers regulate the metabolism of isolated fat cells in vitro

Braz. j. med. biol. res; 49 (8), 2016
Due to the presence of the renin-angiotensin system (RAS) in tissues and its specific influence on white adipose tissue, fat cells are possible targets of pharmacological RAS blockers commonly used as anti-hypertensive drugs. In the present study, we investigated the effects of different RAS blockers on ...

Lipoblastoma benigno de membro superior: relato de caso e revisão da literatura

Rev. bras. cir. plást; 29 (3), 2014
O lipoblastoma é um tumor mesenquimal raro, composto de lipoblastos que continuam sua proliferação após o período pós-natal e que acometem, predominantemente, a população pediátrica. Apresenta prognóstico excelente, apesar do potencial de invasão local e do crescimento rápido. Os autores rela...

Esquema de restriçäo alimentar altera a resposta celular à insulina em ratos diabéticos
Scheme of food restriction change the cellular response to insulin in rats

A resistência à insulina é um elemento chave na gênese de várias alterações fisiopatológicas. O esquema de restrição alimentar meal-feeding (MF) consiste na oferta de uma única refeição diária de 2h, sem, contudo, limitar a quantidade de alimento durante esse período. Este esquema determin...

Tecido adiposo como glândula endócrina
Fat tissue as endocrine gland

O conceito de que os adipócitos são células secretórias surgiu nos últimos anos. Os adipócitos sintetizam e liberam uma variedade de peptídeos e não-peptídeos, bem com expressam outros fatores além de sua capacidade de depositar e mobilizar triglicerídios, retinóides e colesterol. Estas propr...