Pancreatic β-cell function is inhibited by miR-3666 in type 2 diabetes mellitus by targeting adiponectin
Braz. j. med. biol. res; 52 (6), 2019
Type 2 diabetes mellitus (T2D) is a common endocrine and metabolic disorder, and poses threats to human health worldwide. Recently, microRNAs (miRNAs) have been suggested to play important roles in the pathophysiology of T2D. In this study, we explored the role of miR-3666 in T2D. miR-3666 was significan...
Adiponectina/genética, Adiponectina/metabolismo, Apoptosis, Proliferación Celular, Diabetes Mellitus Tipo 2/metabolismo, Diabetes Mellitus Tipo 2/fisiopatología, Citometría de Flujo, Resistencia a la Insulina/fisiología, Células Secretoras de Insulina/metabolismo, Células Secretoras de Insulina/fisiología, MicroARNs/genética, MicroARNs/metabolismo, Reacción en Cadena en Tiempo Real de la Polimerasa