Results: 2

Glycogen synthase kinase 3ß participates in late stages of Dengue virus-2 infection

Mem. Inst. Oswaldo Cruz; 115 (), 2020
BACKGROUND Viruses can modulate intracellular signalling pathways to complete their infectious cycle. Among these, the PI3K/Akt pathway allows prolonged survival of infected cells that favours viral replication. GSK3β, a protein kinase downstream of PI3K/Akt, gets inactivated upon activation of the...

Nuclei ultrastructural changes of C6/36 cells infected with virus dengue type 2

Biomédica (Bogotá); 38 (supl.2), 2018
ABSTRACT Introduction: Dengue virus replication has been considered mainly cytoplasmic, however, studies indicate that some flaviviruses may use the intranuclear pathway as part of the machinery that the virus uses to increase infection capacity in the host cell. This paper describes alterations at nucl...