ABSTRACT Introduction: We have previously shown that some patients present thrombocytopenia (less than 100 × 109/L platelets) in non-alcoholic fatty liver disease (NAFLD). To further explore the nature of this association, we have now analyzed the association of thrombocytopenia with neutropenia (less ...
The Nelore breed is the second largest bovine breed in the world and has actively participated in the expansion of new Brazilian agricultural frontiers. In this context, the purpose of this study was to determine the hematological and biochemical reference intervals of healthy Nelore matrices raised unde...
Resumen La agranulocitosis asociada al consumo de cocaína es un fenómeno vinculado a la presencia de levamisol, un agente antihelmíntico e inmunomodulador, usado como adulterante de la cocaína. Esta reacción puede presentarse con mayor frecuencia en personas con HLA B27. Además de la agranulocitosi...
Se estudió una paciente de 33 años de edad con antecedentes patológicos de Bocio tiroideo difuso desde hace 8 años, que acude al cuerpo de guardia por presentar falta de aire, fiebre de 39-40 °C, dolor de garganta y palpitaciones hace alrededor de tres días. Al examen físico se le constató exofta...
Dipyrone (or metamizole) is an analgesic and antipyretic for oral or parenteral administration. Its action mechanism is directly related to the inhibition of the signaling of TRPA1 (Transient Receptor Potential Ankirin 1). The TRPA1 ion channel, located in the plasma membrane of a subpopulation of nocice...
Rabelo, Patrícia Novais;
Rabelo, Paula Novais;
Paula, Allyne Fernanda de;
Conceição, Samuel Amanso da;
Viggiano, Daniela Pultrini Pereira de Oliveira;
Antunes, Daniela Espíndola;
Jatene, Estela Muszkat;
Paula, Sílvia Leda França Moura de;
Dias, Monike Lourenço;
Reis, Maria Aparecida Lopes.
SUMMARY INTRODUCTION: Graves' disease (GD) is an autoimmune disorder characterized by hyperthyroidism. Antithyroid drugs (ATDs) are available as therapy. Agranulocytosis is a rare but potentially fatal complication of this therapy. In this study, we report agranulocytosis induced by propylthiouracil (PT...
Abstract Introduction: Dipyrone has been positioned in several countries as one of the first over-the-counter options for pain management. Its possible adverse effects are known worldwide; among them, agranulocytosis is the most lethal, with a mortality of approximately 10% and an associated risk of 1 p...
Agranulocitosis/inducido químicamente,
Agranulocitosis/tratamiento farmacológico,
Antibacterianos/uso terapéutico,
Dapsona/efectos adversos,
Quimioterapia Combinada/efectos adversos,
Fármacos Hematológicos/uso terapéutico,
Leprostáticos/efectos adversos,
Lepra Tuberculoide/complicaciones,
Lepra Tuberculoide/tratamiento farmacológico,
Factores de Riesgo,
Resultado del Tratamiento
Se realizó un estudio descriptivo y transversal de 330 pacientes con cáncer, atendidos en el Hospital Oncológico Conrado Benítez de Santiago de Cuba, desde junio hasta diciembre del 2014, para determinar la presencia de neutropenias inducidas por quimioterapia. Presentaron esa afección 145 pacientes...
