The purpose of this work was to elaborate a diagnosis of the dissolution test in Africa in comparison with Brazil, evaluating the dissolution profile of low solubility drugs such as albendazole, ibuprofen, furosemide, glibenclamide, hydrochlorothiazide and carvedilol to ascertain their quality. The disso...
Disolución,
África/etnología,
Brasil/etnología,
Preparaciones Farmacéuticas/análisis,
Solubilidad,
Carvedilol/farmacología,
Albendazol/farmacología,
Acetatos/efectos adversos,
Furosemida/farmacología,
Ibuprofeno,
Métodos,
United States Food and Drug Administration
BACKGROUND It was previously demonstrated that CMC-20, a nitazoxanide and N-methyl-1H-benzimidazole hybrid molecule, had higher in vitro activity against Giardia intestinalis WB strain than metronidazole and albendazole and similar to nitazoxanide. OBJETIVES To evaluate the in vitro activity of CMC-20...
Albendazol/química,
Albendazol/farmacología,
Antiprotozoarios/química,
Antiprotozoarios/farmacología,
Proteínas del Citoesqueleto/efectos de los fármacos,
Técnica del Anticuerpo Fluorescente Indirecta,
Giardia lamblia/efectos de los fármacos,
Pruebas de Sensibilidad Parasitaria,
Tiazoles/química,
Tiazoles/farmacología,
Factores de Tiempo
BACKGROUND It was previously demonstrated that CMC-20, a nitazoxanide and N-methyl-1H-benzimidazole hybrid molecule, had higher in vitro activity against Giardia intestinalis WB strain than metronidazole and albendazole and similar to nitazoxanide. OBJETIVES To evaluate the in vitro activity of CMC-20...
Albendazol/química,
Albendazol/farmacología,
Antiprotozoarios/química,
Antiprotozoarios/farmacología,
Proteínas del Citoesqueleto/efectos de los fármacos,
Técnica del Anticuerpo Fluorescente Indirecta,
Giardia lamblia/efectos de los fármacos,
Pruebas de Sensibilidad Parasitaria,
Tiazoles/química,
Tiazoles/farmacología,
Factores de Tiempo
Abstract Cyathostomins are the most prevalent nematodes of horses, and multidrug resistance has been reported worldwide. There is a need to implement alternative drug monitoring analytical tests. The objective of this study was to determine the consistency (5 repetitions) of the larval migration on agar ...
Abstract The fast anthelmintic resistance development has shown a limited efficiency in the control of animal's endoparasitosis and has promoted research using alternative control methods. The use of chemicals in animal anthelmintic treatment, in association with nematophagous fungi used for biological c...
Abstract The use of biological agents has been intensified in recent years against eggs and larvae of gastrointestinal nematodes as an alternative control method in pasture plant health management, with the concomitant use with antiparasitic drugs still occurring. The aim of this study was to test the in...
Two simple, rapid and inexpensive spectrophotometric methods are described for the determination of albendazole (ALB) in bulk drug and in tablets. The methods are based on charge-transfer (CT) complexation reaction involving ALB as n-donor and iodine as σ-acceptor (method A) in dichloromethane or pi...
El objetivo del presente trabajo fue caracterizar morfológica, morfométrica y estereológicamente las alteraciones causadas por la administración de albendazol en ratas preñadas en el hígado de los fetos. Fueron usadas ratas Wistar, que recibieron entre los días 9 y 11 de la preñez, una dosis diar...
El objetivo de la presente investigación es la de presentar los resultados tras 13 años de uso del Albendazol en concomitancia a la cirugía, con el fin de disminuir la recidiva hidatídica. Con tal propósito, es que desde marzo de 1985 hemos utilizado el Albendazol en 43 pacientes, siendo 14 de ellos...
O albendazol é um potente anti-helmíntico benzimidazólico largamente utilizado em helmintíase intestinal humana, sendo também o medicamento de escolha no tratamento de cisto hidático e neurocisticercose. Apesar de amplamente estudado do ponto de vista clínico, existem poucas referências a respeit...
