LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

6-Gingerol inhibits hair cycle via induction of MMP2 and MMP9 expression

HOU, CHUN; MIAO, YONG; JI, HANG; WANG, SUSHENG; LIANG, GANG; ZHANG, ZHIHUA; HONG, WEIJIN.

An. acad. bras. ciênc; 89 (4), 2017

ABSTRACT 6-Gingerol is the major active constituent of ginger. In the current study, we aimed to investigate the mechanisms underlying the effects of 6-Gingerol on hair growth. Mice were randomly divided into five groups; after hair depilation (day 0), mice were treated with saline, or different concentr...

Catecoles/farmacología, Inducción Enzimática, Alcoholes Grasos/farmacología, Factor 7 de Crecimiento de Fibroblastos/biosíntesis, Folículo Piloso/efectos de los fármacos, Folículo Piloso/patología, Factor I del Crecimiento Similar a la Insulina/biosíntesis, Metaloproteinasa 2 de la Matriz/biosíntesis, Metaloproteinasa 9 de la Matriz/biosíntesis, Ratones Endogámicos C57BL, Extractos Vegetales/farmacología, Distribución Aleatoria, Factor de Crecimiento Transformador beta/biosíntesis, Factor A de Crecimiento Endotelial Vascular/biosíntesis

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Antiproliferative evaluation of tall-oil docosanol and tetracosanol over CHO-K1 and human melanoma cells

Background Polycosanols derived from plant species have traditionally been used in medicine as antiproliferative agents for treating various viruses (primarily the herpes simplex virus). However, few studies have studied their effects on hyperproliferative cell lines. In this work, the antiproliferative ...