Results: 10

Expression of AIF, PARP, and miRNAs MIR-145, MIR-210, and MIR-486 associated with apoptosis in the corpus cavernosum of rats subjected to chronic alcoholism model

Int. j. morphol; 38 (6), 2020
SUMMARY: Previous studies from our group described the consequences of using ethanol on penile erection. Nevertheless, the molecular mechanisms surrounding microRNAs, apoptosis process and their relationship with erectile dysfunction associated with alcohol consumption are still poorly understood. The ob...

AIF, PARP-1 and MicroRNA-9 expression in cerebral ischemia associated to alcoholism experimental model

Int. j. morphol; 38 (3), 2020
The chronic consumption of alcohol causes a worsening of the events that follow the cerebral ischemia. These events are regulated through the expression of several genes and microRNAs. The aimof this work was To analyze and describe the expression profile of PARP and AIF and miRNA-9 proteins in rats subm...

Morphological and immunohistochemical analysis of proteins CASPASE 3 and XIAP in rats subjected to cerebral ischemia and chronic alcoholism

Acta cir. bras; 33 (8), 2018
Abstract Purpose: To evaluate histopathological and ultrastructural changes and expression of proteins related to apoptosis CASPASE 3 and XIAP after experimental induction of temporary focal cerebral ischemia (90 minutes) due to obstruction of the middle cerebral artery in alcoholism model. Methods: F...

Expression profiles of eNOS, iNOS and microRNA-27b in the corpus cavernosum of rats submitted to chronic alcoholism and Diabetes mellitus

Acta cir. bras; 32 (1), 2017
Abstract Purpose: To evaluate the expression of endothelial and inducible NOS in addition to the miRNA-27b in the corpus cavernosum and peripheral blood of healthy rats, diabetic rats, alcoholic rats and rats with both pathologies. Methods: Forty eight Wistar rats were divided into four groups: control...

Morphological and immunohistochemical analysis of apoptosis in the cerebellum of rats subjected to focal cerebral ischemia with or without alcoholism model

Acta cir. bras; 31 (9), 2016
ABSTRACT PURPOSE: To evaluated histopathological changes, morphometric and expression of proteins CASPASE-3, BCL-2 and XIAP related to apoptosis in the cerebellum after induction of temporary focal cerebral ischemia followed by reperfusion, with or without a model of chronic alcoholism. METHODS: Fifty ...

Hipoinsulinemia em alcoolistas com hepatopatia mínima
Hypoinsulinemia in alcoholics with minimal liver disease

OBJETIVO: Em alcoolistas portadores de lesões hepáticas mínimas avaliar os níveis de glicose e insulina séricas após estímulo com glicose intravenosa. MÉTODOS: Em oito etilistas, portadores de alterações hepáticas mínimas, caracteriza por biópsia hepática, e em 26 controles sadios não-alco...

Vantagens e limitacoes do uso da urina como amostra biologica na dosagem alcoolica
Advantages and limitations in the use of urine as biological sample in the alcoholic dosage

Tendo em vista o grande interesse do uso da urina nos programas de controle e prevencao do uso de alcool e drogas no ambiente de trabalho e nas clinicas de reabilitacao, surge a necessidade de estudos mais detalhados sobre o fator de conversao utilizado para tranformar os valores de concentracao urinaria...

Alteraciones Metabolicas en el Alcoholismo
Metabolic disorders in alcoholism

Rev. cuba. aliment. nutr; 10 (1), 1996
La ingestion sostenida de alcohol genera a nivel intermediario cambios metabolicos que favorecen la aparicion de dano hepatico grave y disfuncion del transporte axonal que decursa hacia una neuropatia axonal periferica. La malnutricion, primaria o secundaria, vinculada al alcoholismo tiene manifestacione...