Results: 9

Molecular characterization and functional analysis of scavenger receptor class B from black tiger shrimp (Penaeus monodon)

BACKGROUND: Scavenger receptor class B (SRB) is a multifunctional protein in animals that participates in physiological processes, including recognition of a wide range of ligands. Astaxanthin is a major carotenoid found in shrimp. However, the molecular mechanism of astaxanthin and SRB protein binding h...

RNA-seq analysis of the response of plant-pathogenic oomycete Phytophthora parasitica to the fungicide dimethomorph

Rev. argent. microbiol; 51 (3), 2019
Phytophthora parasitica is an important oomycete that causes disease in a variety of plants, dimethomorph fungicides being specific for oomycetes. The aim of this study was to use RNA-seq to rapidly discover the mechanism by which dimethomorph acts in the treatment of P. parasitica. We found that the exp...

Especies de flebotomíneos (Diptera: Psychodidae) recolectados en reservas naturales de las regiones del Darién y del Pacífico en Colombia

Biomédica (Bogotá); 37 (supl.2), 2017
Resumen Introducción. Los departamentos de Chocó y Antioquia en Colombia presentan condiciones climáticas y de vegetación que favorecen el establecimiento de especies de vectores del género Lutzomyia y la transmisión de Leishmania spp. a poblaciones humanas que ingresan a ambientes selváticos co...

Genome analysis of yellow fever virus of the ongoing outbreak in Brazil reveals polymorphisms

Mem. Inst. Oswaldo Cruz; 112 (6), 2017
The current yellow fever outbreak in Brazil is the most severe one in the country in recent times. It has rapidly spread to areas where YF virus (YFV) activity has not been observed for more than 70 years and vaccine coverage is almost null. Here, we sequenced the whole YFV genome of two naturally infect...

Epidemiologia da leishmaniose tegumentar americana (LTA) no município de Xapuri, Estado do Acre, Brasil: estudo em população humana, cães domésticos e vetores

Introdução. A leishmaniose tegumentar americana (LTA) é uma endemia de importância em saúde pública na Amazônia Brasileira, onde possui diferentes perfis de transmissão com a participação de diversas espécies de vetores e de protozoários do gênero Leishmania. O Estado do Acre apresenta altos...

Isolation and expression of two polyketide synthase genes from Trichoderma harzianum 88 during mycoparasitism

Braz. j. microbiol; 47 (2), 2016
Abstract Metabolites of mycoparasitic fungal species such as Trichoderma harzianum 88 have important biological roles. In this study, two new ketoacyl synthase (KS) fragments were isolated from cultured Trichoderma harzianum 88 mycelia using degenerate primers and analysed using a phylogenetic tree. The ...

The accuracy of protein structure alignment servers

Electron. j. biotechnol; 19 (2), 2016
Background: Protein structural alignment is one of the most fundamental and crucial areas of research in the domain of computational structural biology. Comparison of a protein structure with known structures helps to classify it as a new or belonging to a known group of proteins. This, in turn, is usefu...

Evaluation of computer methods for biomarker discovery on computational grids

Electron. j. biotechnol; 16 (5), 2013
Background: Discovering biomarkers is a fundamental step to understand and deal with genetic diseases. Methods using classic Computer Science algorithms have been adapted in order to support processing large biological data sets, aiming to find useful information to understand causing conditions of disea...

The molecular characterization of a cyclophilin A from Chinese mitten crab Eriocheir sinensis and the antifungal activity of its recombinant protein

Electron. j. biotechnol; 16 (2), 2013
Background: Cyclophilin A (CypA), a receptor for the immunosuppressive agent cyclosporin A (CsA), is a cis-trans peptidyl-prolyl isomerase (PPIase) which accelerates the cis-trans isomerization of prolyl-peptide bonds and interacts with a variety of proteins to regulate their activities. Results: The ful...