Prostaglandin A1 triggers Mayaro virus inhibition and heat shock protein 70 expression in an epithelial cell model
Rev. Soc. Bras. Med. Trop; 51 (5), 2018
Abstract INTRODUCTION: The Mayaro virus (MAYV), which is an arbovirus closely related to the Chikungunya virus, causes a dengue-like acute illness that is endemic to Central and South America. We investigated the anti-MAYV activity of prostaglandin A1 (PGA1), a hormone which exhibits antiviral activity...
Alphavirus/efectos de los fármacos, Alphavirus/ultraestructura, Antivirales/farmacología, Western Blotting, Línea Celular, Electroforesis en Gel de Poliacrilamida, Células Epiteliales/ultraestructura, Células Epiteliales/virología, Proteínas HSP70 de Choque Térmico/farmacología, Microscopía Electrónica de Transmisión, Prostaglandinas A/farmacología, Replicación Viral/efectos de los fármacos