A review of experimental models in colorectal carcinogenesis
J. coloproctol. (Rio J., Impr.); 36 (1), 2016
Colorectal cancer is the leading cause of malignancy of the gastrointestinal tract. A better understanding of the molecular and cellular changes that lead to the disease is necessary to develop early diagnosis and optimal treatment modalities. Rodent models are rapid, reproducible and exhibit an adenoma-...
Inmunohistoquímica, Endoscopía, Neoplasias Colorrectales/diagnóstico, Neoplasias Colorrectales/genética, Modelos Animales, Modelos Animales de Enfermedad, Biomarcadores Ambientales, Carcinogénesis/química, 1,2-Dimetilhidrazina, Azoximetano/química, Ácidos Heterocíclicos, Aminoácidos Aromáticos, Alquilación