The role of NMDA receptor antagonists, amantadine and memantine, in schizophrenia treatment: a systematic review
Arch. Clin. Psychiatry (Impr.); 46 (6), 2019
Abstract Objective Schizophrenia is a complex and chronic psychiatric disorder. In recent years, studies have found glutamatergic system participation in its etiopathogenesis, especially through aberrant NMDA receptors functioning. Thus, drugs that modulate this activity, as amantadine and memantine, co...
Esquizofrenia/tratamiento farmacológico, Amantadina/uso terapéutico, Memantina/uso terapéutico, Receptores de N-Metil-D-Aspartato/antagonistas & inhibidores, Método Doble Ciego, Placebos, Escalas de Valoración Psiquiátrica, Adyuvantes Anestésicos/uso terapéutico, Antipsicóticos/uso terapéutico, Resultado del Tratamiento, Amantadina/efectos adversos, Memantina/efectos adversos, PubMed