LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Exfoliation syndrome associated with LOXL1 gene polymorphisms in a Black patient from Latin America: a case report

Takitani, Guilherme Eiichi da Silva; Azevedo, Alexandre Gomes Bortoloti de; Motta, Fabiana Louise; Teixeira, Sérgio Henrique; Sallum, Juliana Maria Ferraz; Vessani, Roberto Murad.

Arq. bras. oftalmol; 81 (5), 2018

ABSTRACT A 89-year-old Black female with a 6-year history of advanced open-angle glaucoma was referred to the Glaucoma Service of the Ophthalmology Department - Federal University of São Paulo (UNIFESP). Best-corrected visual acuity was 20/400 in the right eye and 20/60 in the left eye. Pseudoexfoliatio...

Población Negra, Aminoácido Oxidorreductasas/genética, Síndrome de Exfoliación/diagnóstico por imagen, Síndrome de Exfoliación/genética, Frecuencia de los Genes, Predisposición Genética a la Enfermedad, Polimorfismo de Nucleótido Simple

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Asn336 is involved in the substrate affinity of glycine oxidase from Bacillus cereus

Background: Glycine oxidase (GO), a type of D-amino acid oxidase, is of biotechnological interest for its potential in several fields. In our previous study, we have characterized a new glycine oxidase (BceGO) from Bacillus cereus HYC-7. Here, a variant of N336K with increased the affinity against all th...