Impact of dexmedetomidine on amino acid contents and the cerebral ultrastructure of rats with cerebral ischemia-reperfusion injury
Acta cir. bras; 32 (6), 2017
Abstract Purpose: To investigate the effects of dexmedetomidine (DEX) on amino acid contents and the cerebral ultrastructure of rats with cerebral ischemia-reperfusion injury (I/R). Methods: Thirty-six, male, Wistar rats were randomly divided into three groups: the sham operation group (group C), the i...
Aminoácidos/efectos de los fármacos, Aminoácidos/metabolismo, Isquemia Encefálica/tratamiento farmacológico, Isquemia Encefálica/metabolismo, Corteza Cerebral/química, Corteza Cerebral/ultraestructura, Dexmedetomidina/farmacología, Glutamina/metabolismo, Fármacos Neuroprotectores/farmacología, Ratas Wistar, Daño por Reperfusión/metabolismo, Ácido gamma-Aminobutírico/efectos de los fármacos, Ácido gamma-Aminobutírico/metabolismo