Development of monolithic matrix type transdermal patches containing cinnarizine: Physical characterization and permeation studies
Braz. J. Pharm. Sci. (Online); 58 (), 2022
To overcome the problems associated with bioavailability and systemic side effects of the drug by oral administration, monolithic matrix type transdermal patches containing cinnarizine (CNZ) were developed. For this purpose, films based on hydroxypropyl methylcellulose and polyvinylpyrrolidone as matrix-...