Xu, Yan;
Xie, Chuang Bo;
Yang, Jing;
Xing, Yong Ji;
Xia, Wei Ping;
Liu, Yang;
Xi, Wen Bin;
Li, Zhao Ju;
Tu, Wei Feng;
Zhang, Jun Long.
Abstract Introduction: Propofol is a widely used anesthetic and its dose is closely related to aging. Telomere length (TL) is a unique heritable trait, and emerging as a biomarker of aging, health and disease. Telomerase RNA component (TERC) plays an important role in maintaining TL. We proposed a hypot...
Abstract Background: Our objective was to compare the safety and efficacy of Target-Controlled Infusion (TCI) versus intermittent bolus of propofol for colonoscopy sedation. Methods: We conducted a randomized (1:1), single-blind, parallel-group superiority trial with fifty ASA I or II patients, both se...
Abstract Background Melatonin has been studied to have anxiolytic, sedative, and analgesic effects. However, there is limited data on the effect of melatonin in the attenuation of hemodynamic response to intubation. We aimed to study whether preanesthetic oral melatonin attenuates hemodynamic responses ...
Introducción: En los últimos años la anestesia libre de opioides ha constituido una alternativa más a las técnicas tradicionales de anestesia general. Con la exclusión de este grupo de fármacos se evitan los múltiples efectos adversos y complicaciones asociados al mismo. A pesar de que la anestes...
In Uruguay, after cardiovascular diseases, cáncer ranks second as a cause of death. According to official data from the Ministry of Public Health in 2017, 24.6% of deaths were due to this disease. In our specialty, there is great concern about the evolutionary consequences of neoplastic disease related ...
In emergency settings, TIVA should be adjusted in accordance to the pharmacological changes observed in the hypovolemic patient. With the understanding that in those cases there is a decrease in drug requirements, there is a tendency to underdose these patients, increasing the possibility of awareness. V...
Total intravenous anesthesia (TIVA) with propofol/remifentanil appears in the literatura as a good option for neurosurgical patients who have increased intracranial pressure (ICP),risk of postoperative nausea and vomiting (PONV), need for neuromonitoring, and in those with impaired brain self-regulation....
Abstract Background and objectives Day-case pediatric sedation is challenging. Dexmedetomidine is a sedative analgesic that does not induce respiratory depression. We compared dexmedetomidine to propofol when it was added to ketamine for sedation during pediatric endoscopy, regarding recovery time and h...
Analgésicos/administración & dosificación,
Periodo de Recuperación de la Anestesia,
Anestésicos Combinados/administración & dosificación,
Anestésicos Intravenosos/administración & dosificación,
Presión Sanguínea/efectos de los fármacos,
Dexmedetomidina/administración & dosificación,
Endoscopía Gastrointestinal,
Frecuencia Cardíaca/efectos de los fármacos,
Hipnóticos y Sedantes/administración & dosificación,
Hipotensión/inducido químicamente,
Ketamina/administración & dosificación,
Oxígeno/sangre,
Propofol/administración & dosificación,
Factores de Tiempo
Abstract Introduction and objectives: The incidence of Postoperative Nausea and Vomiting (PONV) after video cholecystectomy is high. Progress in pharmacological PONV prophylaxis includes a new generation of 5-HT3 antagonists. This study aims to assess the effect of the 5-HT3 antagonist in postanesthetic...
Anestésicos Intravenosos/administración & dosificación,
Antieméticos/administración & dosificación,
Colecistectomía Laparoscópica/métodos,
Dexametasona/administración & dosificación,
Método Doble Ciego,
Persona de Mediana Edad,
Ondansetrón/administración & dosificación,
Palonosetrón/administración & dosificación,
Náusea y Vómito Posoperatorios/prevención & control,
Propofol/administración & dosificación,
Remifentanilo/administración & dosificación,
Rocuronio/administración & dosificación
Abstract Background: Postoperative Nausea and Vomiting (PONV) is a multifactorial surgical complication with an unclear underlying cause. Anesthetic methods, patients' characteristics and the type of surgery are considered as factors affecting PONV. This study was designed to compare the effect of inhal...
Abdomen/cirugía,
Anestésicos por Inhalación/administración & dosificación,
Anestésicos por Inhalación/efectos adversos,
Anestésicos Intravenosos/administración & dosificación,
Anestésicos Intravenosos/efectos adversos,
Antieméticos/administración & dosificación,
Incidencia,
Laparotomía/métodos,
Persona de Mediana Edad,
Náusea y Vómito Posoperatorios/epidemiología,
Índice de Severidad de la Enfermedad,
Método Simple Ciego
